Evidence map›Paper›PMID 32907350›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

The Burden of Unnecessary Testing From a Regularly Ordered Laboratory Assay: Age-Adjusted d-Dimer Quality Improvement Study.

Marcel M Letourneau, Marc Zughaib, Abeer Berry, Marcel Zughaib

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marcel M LetourneauDepartment of Cardiovascular Medicine, 7432Ascension Providence Hospital, Southfield, MI, USA.ORCID https://orcid.org/0000-0002-3865-5112
Marc Zughaib43977Mighigan State University College of Osteopathic Medicine, East Landing, MI, USA.
Abeer BerryDepartment of Cardiovascular Medicine, 7432Ascension Providence Hospital, Southfield, MI, USA.
Marcel ZughaibDepartment of Cardiovascular Medicine, 7432Ascension Providence Hospital, Southfield, MI, USA.
Ascension Providence Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosing acute pulmonary embolism (PE) involves clinical suspicion in combination with sequential diagnostic tests including d-dimer laboratory assays. Although the sensitivity of this assay is well validated and thoroughly tested, a false-positive result can lead to unnecessary and costly testing. The age-adjusted d-dimer (AADD) has been suggested in the literature to improve the usefulness of d-dimer cutoffs and safely decrease iodine and radiation exposure associated with definitively ruling out PE with computed tomographic angiography (CTA).

Indexed as

AgedAged, 80 and overBiomarkersFemaleFibrin Fibrinogen Degradation ProductsHumansLaboratoriesMaleMiddle AgedPulmonary EmbolismQuality ImprovementRetrospective StudiesBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment Dbiomarkersdiagnosispulmonary embolismrisk assessment

Identifiers

PMID32907350
PMCPMC7493266
OpenAlexW3085471079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.