ArticleMicromachines2020
Changes of Inertial Focusing Position in a Triangular Channel Depending on Droplet Deformability and Size.
Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Deciphering viscoelastic cell manipulation in rectangular microchannels.Physics of fluids (Woodbury, N.Y. : 1994) · 2023Article
- A Continuous Microfluidic Concentrator for High-Sensitivity Detection of Bacteria in Water Sources.Micromachines · 2022Article
- Numerical simulations of viscoelastic particle migration in a microchannel with triangular cross-section.Electrophoresis · 2021Article
- Editorial for the Special Issue on Inertial Microfluidics.Micromachines · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Studies on cell separation with inertial microfluidics are often carried out with solid particles initially. When this condition is applied for actual cell separations, the efficiency typically becomes lower because of the polydispersity and deformability of cells. Therefore, the understanding of deformability-induced lift force is essential to achieve highly efficient cell separation. We investigate the inertial focusing positions of viscous droplets in a triangular channel while varying Re, deformability, and droplet size. With increasing Re and decreasing droplet size, the top focusing position splits and shifts along the sidewalls. The threshold size of the focusing position splitting increases for droplets with larger deformability. The overall path of the focusing position shifts with increasing Re also has a strong dependency on deformability. Consequently, droplets of the same size can have different focusing positions depending on their deformability. The feasibility of deformability-based cell separation is shown by different focusing positions of MCF10a and MCF7 cells.
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Registered trials
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