Evidence map›Paper›PMID 32906772›Full record

ReviewMolecules (Basel, Switzerland)2020

Design of Bio-Conjugated Hydrogels for Regenerative Medicine Applications: From Polymer Scaffold to Biomolecule Choice.

Vittoria Chimisso, Miguel Angel Aleman Garcia, Saziye Yorulmaz Avsar, Ionel Adrian Dinu, Cornelia G Palivan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Gels (Basel, Switzerland) · 2023
    Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vittoria ChimissoDepartment of Chemistry, University of Basel, Mattenstrasse 24a, BPR-1096, 4058 Basel, Switzerland.
Miguel Angel Aleman GarciaDepartment of Chemistry, University of Basel, Mattenstrasse 24a, BPR-1096, 4058 Basel, Switzerland.
Saziye Yorulmaz AvsarDepartment of Chemistry, University of Basel, Mattenstrasse 24a, BPR-1096, 4058 Basel, Switzerland.
Ionel Adrian DinuDepartment of Chemistry, University of Basel, Mattenstrasse 24a, BPR-1096, 4058 Basel, Switzerland.
Cornelia G PalivanDepartment of Chemistry, University of Basel, Mattenstrasse 24a, BPR-1096, 4058 Basel, Switzerland.ORCID 0000-0001-7777-5355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bio-conjugated hydrogels merge the functionality of a synthetic network with the activity of a biomolecule, becoming thus an interesting class of materials for a variety of biomedical applications. This combination allows the fine tuning of their functionality and activity, whilst retaining biocompatibility, responsivity and displaying tunable chemical and mechanical properties. A complex scenario of molecular factors and conditions have to be taken into account to ensure the correct functionality of the bio-hydrogel as a scaffold or a delivery system, including the polymer backbone and biomolecule choice, polymerization conditions, architecture and biocompatibility. In this review, we present these key factors and conditions that have to match together to ensure the correct functionality of the bio-conjugated hydrogel. We then present recent examples of bio-conjugated hydrogel systems paving the way for regenerative medicine applications.

Indexed as

Regenerative MedicineAnimalsBiocompatible MaterialsChemical PhenomenaHumansHydrogelsMechanical PhenomenaPolymersTissue EngineeringTissue ScaffoldsBiocompatible MaterialsHydrogelsPolymersbio-conjugated hydrogelsbiomoleculepolymer scaffoldregenerative medicine

Identifiers

PMID32906772
PMCPMC7571016

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.