Evidence map›Paper›PMID 32906736›Full record

ReviewInternational journal of environmental research and public health2020

Forest Volatile Organic Compounds and Their Effects on Human Health: A State-of-the-Art Review.

Michele Antonelli, Davide Donelli, Grazia Barbieri, Marco Valussi, Valentina Maggini, Fabio Firenzuoli

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 5 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 5 syntheses or guidelines pooled it, 218 citations in OpenAlex.

  1. Pooled it
  2. Effects of Forest-Based Interventions on Mental Health: A Meta-Analysis of Randomized Controlled Trials.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
  4. Effect of Forest Therapy on Depression and Anxiety: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021
    Pooled it
  5. Pooled it
  6. Smelling Wellness: Associations Between Botanic Garden Scentscapes and Human Health Gains.International journal of environmental research and public health · 2026
    Trial
  7. Trial
  8. Effects of Urban Forest Therapy Program on Depression Patients.International journal of environmental research and public health · 2022
    Trial
  9. Cardiorespiratory Interaction and Autonomic Sleep Quality Improve during Sleep in Beds Made fromInternational journal of environmental research and public health · 2021
    Trial
  10. The forest as a health-promoting place-the meaning for seniors of playing padel in the forest: a qualitative study.International journal of qualitative studies on health and well-being · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Nature prescription for patients with chronic respiratory diseases.The World Allergy Organization journal · 2026
    Review
  17. Review
  18. Article
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Michele AntonelliTerme di Monticelli, 43022 Monticelli Terme PR, Italy.
Davide DonelliCERFIT, Careggi University Hospital, 50139 Firenze FI, Italy.ORCID 0000-0002-7895-2840
Grazia BarbieriBinini Partners S.r.l. Engineering and Architecture, 42121 Reggio Emilia RE, Italy.
Marco ValussiEuropean Herbal and Traditional Medicine Practitioners Association (EHTPA), Norwich NR3 1HG, UK.
Valentina MagginiCERFIT, Careggi University Hospital, 50139 Firenze FI, Italy.
Fabio FirenzuoliCERFIT, Careggi University Hospital, 50139 Firenze FI, Italy.ORCID 0000-0003-1911-2021
Azienda Ospedaliero-Universitaria Careggi · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this research work is to analyze the chemistry and diversity of forest VOCs (volatile organic compounds) and to outline their evidence-based effects on health. This research work was designed as a narrative overview of the scientific literature. Inhaling forest VOCs like limonene and pinene can result in useful antioxidant and anti-inflammatory effects on the airways, and the pharmacological activity of some terpenes absorbed through inhalation may be also beneficial to promote brain functions by decreasing mental fatigue, inducing relaxation, and improving cognitive performance and mood. The tree composition can markedly influence the concentration of specific VOCs in the forest air, which also exhibits cyclic diurnal variations. Moreover, beneficial psychological and physiological effects of visiting a forest cannot be solely attributed to VOC inhalation but are due to a global and integrated stimulation of the five senses, induced by all specific characteristics of the natural environment, with the visual component probably playing a fundamental role in the overall effect. Globally, these findings can have useful implications for individual wellbeing, public health, and landscape design. Further clinical and environmental studies are advised, since the majority of the existing evidence is derived from laboratory findings.

Indexed as

Air PollutantsEnvironmental HealthTreesVolatile Organic CompoundsEnvironmental MonitoringForestsHumansAir PollutantsVolatile Organic Compoundsbiogenic volatile organic compoundsforestlimonenephytoncidespinenepreventive medicinepublic healthreview

Identifiers

PMID32906736
PMCPMC7559006
OpenAlexW3083518526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.