Evidence map›Paper›PMID 32906723›Full record

ArticleMaterials (Basel, Switzerland)2020

pH-Responsive and Biodegradable ZnO-Capped Mesoporous Silica Composite Nanoparticles for Drug Delivery.

Minmin Chen, Jinxia Hu, Cancan Bian, Chenghao Zhu, Chen Chen, Zhijun Guo, Zhimin Zhang, Godfred Amfo Agyekum, Zhuoqi Zhang, Xichuan Cao

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Zinc Oxide Nanoparticles as Drug Delivery Tools.Materials (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Minmin ChenSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
Jinxia HuSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
Cancan BianSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
Chenghao ZhuSchool of Chemical Engineering and Technology, China University of Mining and Technology, Xuzhou 221116, China.
Chen ChenSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
Zhijun GuoSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
Zhimin ZhangSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
Godfred Amfo AgyekumDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China.
Zhuoqi ZhangDepartment of Cardiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China.
Xichuan CaoSchool of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
China University of Mining and Technology · CNXuzhou Medical College · CN

Funding

Fundamental Research Funds for the Central Universities 2018BSCXB11Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX18_1937
6 · The paper itself

Abstract

As a drug delivery system (DDS), traditional mesoporous silica nanoparticles (MSNs) suffer from bioaccumulation in vivo and premature drug release in systemic circulation due to low degradation rate and lack of protective gatekeeper. Herein, we developed a safe and intelligent DDS with characteristics of pH-responsive biodegradation and controlled drug release based on mesoporous silica composite nanoparticles (MSCNs) capped with ZnO quantum dots (ZnO QDs). Acidic degradable MSCNs were successfully synthesized by doping Ca

Indexed as

mesoporous silica composite nanoparticles (MSCNs)pH-responsive biodegradabilitypH-responsive drug deliveryZnO QDs

Identifiers

PMID32906723
PMCPMC7558045
OpenAlexW3083035363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.