ArticleCancers2020
Orbital and Eyelid B-Cell Lymphoma: A Multicenter Retrospective Study.
Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Visual prognosis and survival outcomes in patients with ocular adnexal diffuse large B-cell lymphoma.International journal of ophthalmology · 2026Article
- Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report.The American journal of case reports · 2025Article
- Bilateral eyelid masses and enophthalmos as the initial manifestation of diffuse large B-cell lymphoma: a case report.Journal of medical case reports · 2025Article
- Skin Erosion on the Nasal Root with Marked Right Eyelid Swelling: A Quiz.Acta dermato-venereologica · 2025Article
- Ocular adnexal lymphoma - A single-center observational study of survival outcomes.Indian journal of ophthalmology · 2025Observational
- Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease.Frontiers in immunology · 2025Article
- Role of miRNA in adult ocular tumorigenesis.Frontiers in molecular biosciences · 2025Review
- Incidental Diagnosis of Four Lid Orbital Lymphoma during a Blepharoplasty.Plastic and reconstructive surgery. Global open · 2024Article
- Predicting the prognosis of primary orbital lymphoma by clinical characteristics and imaging features.International journal of ophthalmology · 2023Article
- Cutaneous follicle center lymphoma of the eyelids: Unusual location.JAAD case reports · 2022Article
- [Conjunctival mantle cell lymphoma-a therapeutic challenge].Die Ophthalmologie · 2022Article
- Primary unilateral conjunctival small lymphocytic lymphoma in a child: Case report and literature review.Oman journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to analyze patients diagnosed, staged and treated for orbital and eyelid B-cell lymphoma (OEL).
methodsOne hundred and forty-one cases of OEL were included in this study. Primary endpoints were to analyze the histopathologic findings, the main risk factors and the type of treatment and to correlate them with recurrence of OEL. The secondary endpoint was to determine the progression-free survival (PFS) time.
resultsExtranodal marginal zone B-cell lymphoma was the most frequent subtype (66%), followed by small lymphocytic lymphoma (12.7%), diffuse large B-cell lymphoma (DLBCL) (9.2%), follicular lymphoma (6.6%), mantle cell lymphoma (4.3%) and Burkitt lymphoma (1.2%). The probability of relapse was influenced by the histopathologic subtype DLBCL (OR = 7.7, 95% CI 1.8-32.3) and treatment with chemotherapy (OR = 14.9, 95% CI 2.6-83.7). Multivariate analysis showed that the histopathologic subtype DLBCL and chemotherapy treatment retained statistical significance for a poorer PFS, with hazard ratios of 8.581 (
conclusionsFive lymphoma subtypes were found in patients with OEL. The histopathologic subtype and the type of treatment were found to be the main factors influencing treatment outcome.
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