Evidence map›Paper›PMID 32906577›Full record

ReviewMolecules (Basel, Switzerland)2020

Kaempferol as a Dietary Anti-Inflammatory Agent: Current Therapeutic Standing.

Waqas Alam, Haroon Khan, Muhammad Ajmal Shah, Omar Cauli, Luciano Saso

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 7 pooled it
27.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 7 syntheses or guidelines pooled it, 353 citations in OpenAlex.

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  11. Extracellular Vesicles Derived fromNanomaterials (Basel, Switzerland) · 2026
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  20. Marine drugs · 2026
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112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Waqas AlamDepartment of Pharmacy, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
Haroon KhanDepartment of Pharmacy, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.ORCID 0000-0002-1736-4404
Muhammad Ajmal ShahDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad 38000, Pakistan.ORCID 0000-0003-3471-184X
Omar CauliDepartment of Nursing, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-5669-4943
Luciano SasoDepartment of Physiology and Pharmacology "Vittorio Erspamer", Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0003-4530-8706
Abdul Wali Khan University Mardan · PKGovernment College University, Faisalabad · PKUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a physiological response to different pathological, cellular or vascular damages due to physical, chemical or mechanical trauma. It is characterized by pain, redness, heat and swelling. Current natural drugs are carefully chosen as a novel therapeutic strategy for the management of inflammatory diseases. Different phytochemical constituents are present in natural products. These phytochemicals have high efficacy both in vivo and in vitro. Among them, flavonoids occur in many foods, vegetables and herbal medicines and are considered as the most active constituent, having the ability to attenuate inflammation. Kaempferol is a polyphenol that is richly found in fruits, vegetables and herbal medicines. It is also found in plant-derived beverages. Kaempferol is used in the management of various ailments but there is no available review article that can summarize all the natural sources and biological activities specifically focusing on the anti-inflammatory effect of kaempferol. Therefore, this article is aimed at providing a brief updated review of the literature regarding the anti-inflammatory effect of kaempferol and its possible molecular mechanisms of action. Furthermore, the review provides the available updated literature regarding the natural sources, chemistry, biosynthesis, oral absorption, metabolism, bioavailability and therapeutic effect of kaempferol.

Indexed as

Dietary SupplementsAnimalsAnti-Inflammatory AgentsBiological AvailabilityBiological ProductsChemical FractionationFlavonoidsHumansKaempferolsPhytochemicalsPlants, MedicinalStructure-Activity RelationshipToxicity TestsAnti-Inflammatory AgentsBiological ProductsFlavonoidsKaempferolsPhytochemicalsflavonoidsinflammationkaempferoltherapeutic utility

Identifiers

PMID32906577
PMCPMC7570692
OpenAlexW3083159913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.