Evidence map›Paper›PMID 32906123›Full record

ArticleNeuroepidemiology2020

Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer's Disease Center.

David X Marquez, Crystal M Glover, Melissa Lamar, Sue E Leurgans, Raj C Shah, Lisa L Barnes, Neelum T Aggarwal, Aron S Buchman, David A Bennett

Abstract read
In one paragraph

Article in Neuroepidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
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  7. Arachnoid granulation morphologies and β-amyloid and tau pathology in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Sub-Networks of the Brain RHuman brain mapping · 2026
    Article
  12. Article
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  14. Article
  15. Article
  16. Exploring the influence of loneliness on cognitive decline: differential effects in Black and White older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  17. Article
  18. Article
  19. ARTS is associated with vascular risk factors, MCI, dementia, and stroke.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David X MarquezRush Alzheimer's Disease Center, Chicago, Illinois, USA, marquezd@uic.edu.
Crystal M GloverRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Melissa LamarRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Sue E LeurgansRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Raj C ShahRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Lisa L BarnesRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Neelum T AggarwalRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Aron S BuchmanRush Alzheimer's Disease Center, Chicago, Illinois, USA.
David A BennettRush Alzheimer's Disease Center, Chicago, Illinois, USA.

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Racial Differences in Late-Life Cognitive Decline and Risk of Alzheimer's DiseaseRF1AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2016 to 2019
$6.6M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R01 AG062711NIA NIH HHS RF1 AG022018
6 · The paper itself

Abstract

The Rush Alzheimer's Disease Center (RADC) conducts 5 harmonized prospective clinical-pathologic cohort studies of aging - with 1 study, the Latino Core, focused exclusively on Latinxs, 2 studies consisting of mostly non-Latinx whites, and 2 studies of mostly non-Latinx blacks. This paper contextualizes the Latino Core within the other 4 harmonized RADC cohort studies. The overall aim of the paper is to provide information from the RADC, so that researchers can learn from our participants and procedures to better advance the science of Alzheimer's disease and related dementias in Latinxs. We describe an annual clinical evaluation that assesses risk factors for Alzheimer's dementia among older adults without known dementia at enrollment. As all RADC cohort studies offer brain donation as a part of research participation, we discuss our approach to brain donation and subsequent participant decision-making among older Latinxs. We also summarize baseline characteristics of older Latinxs across the 5 RADC cohort studies in relation to the baseline characteristics of non-Latinx blacks and non-Latinx whites. Finally, we outline challenges and considerations as well as potential next steps in cognitive aging research with older Latinxs.

Indexed as

Hispanic or LatinoAgedAged, 80 and overAgingAlzheimer DiseaseBlack or African AmericanBlack PeopleCognitive DysfunctionCohort StudiesFemaleHumansMaleProspective StudiesSelf-AssessmentUnited StatesWhite PeopleAlzheimer’s diseaseCognitionHealth disparitiesLatinx

Identifiers

PMID32906123
PMCPMC7572552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.