Evidence map›Paper›PMID 32905720›Full record

ArticleGlobal spine journal2020

Does Size Matter? An Analysis of the Effect of Lumbar Disc Herniation Size on the Success of Nonoperative Treatment.

Anmol Gupta, Shivam Upadhyaya, Caleb M Yeung, Peter J Ostergaard, Harold A Fogel, Thomas Cha, Joseph Schwab, Chris Bono, Stuart Hershman

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

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  14. Should you adjust that herniated disc? Thoughts from a chiropractor/molecular scientist.The Journal of the Canadian Chiropractic Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anmol GuptaHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0001-8320-740X
Shivam UpadhyayaHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Caleb M YeungHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Peter J OstergaardHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Harold A FogelHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Thomas ChaHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Joseph SchwabHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Chris BonoHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Stuart HershmanHarvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective study.

objectiveIn this study, we examined whether the size of a lumbar disc herniation (LDH) is predictive of the need for surgical intervention within 2 years after obtaining an initial magnetic resonance imaging (MRI) scan. We hypothesized that a fragment that occupied a larger percentage of the spinal canal would not predict which patients failed conservative management.

methodsUsing the ICD-10 code M51.26, we identified patients at a single academic institution, across the 2-year period from 2015 to 2016, who received a diagnosis of primary lumbar radicular pain, had MRI showing a disc herniation, and underwent at least 6 weeks of nonoperative management. Patients experiencing symptoms suggesting cauda equina syndrome and those with progressive motor neurological deficits were excluded from analysis, as were patients exhibiting "hard" disc herniations. Within the axial view of an MRI, the following measurements were made on AGFA-IMPACS for a given disc herniation: the length of both the canal and the herniated disc along the anterior-posterior axis, the average width of the disc within the canal; the total canal area, and the area of the disc herniation. Data analysis was conducted in SPSS and a 2-tailed reliability analysis using Cronbach's alpha as a measure of reliability was obtained.

resultsA total of 368 patients met the inclusion and exclusion criteria for this study. Of these, 14 (3.8%) had L3-L4 herniations, 185 had L4-L5 herniations (50.3%), and 169 had L5-S1 herniations (45.9%). Overall, 336 (91.3%) patients did not undergo surgery within 1 year of the LDH diagnosis. Patients who did not receive surgery had an average herniation size that occupied 31.2% of the canal, whereas patients who received surgery had disc herniations that occupied 31.5% of the canal on average. A Cronbach's alpha of .992 was observed overall across interobserver measurements. After controlling for age, race, gender, and location of herniation through a logistic regression, it was found that the size of the herniation and the percentage of the canal that was occupied had no predictive value with regard to failure of conservative management, generating an odds ratio for surgery of 1.00.

conclusionsThe percentage of the spinal canal occupied by a herniated disc does not predict which patients will fail nonoperative treatment and require surgery within 2 years after undergoing a lumbar spine MRI scan.

Indexed as

back paincauda equina syndromediscectomydisc herniationfailed back surgerylow back painlumbarMRI

Identifiers

PMID32905720
PMCPMC7485083
OpenAlexW2980154296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.