Evidence map›Paper›PMID 32905668›Full record

ArticleThe New England journal of medicine2020

Targeted FGFR Blockade for the Treatment of Tumor-Induced Osteomalacia.

Iris R Hartley, Carole B Miller, Georgios Z Papadakis, Clemens Bergwitz, Jaydira Del Rivero, Jenny E Blau, Pablo Florenzano, Jason A Berglund, Jing Tassone, Kelly L Roszko and 4 more

Abstract readCase ReportsLetter
In one paragraph

Article in The New England journal of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. How I treat soft tissue sarcomas.Future oncology (London, England) · 2026
    Review
  4. Hypophosphatemic rickets: diagnosis and treatment.Archives of endocrinology and metabolism · 2026
    Review
  5. Review
  6. Article
  7. Treatment Advances in Tumor-Induced Osteomalacia.Calcified tissue international · 2025
    Review
  8. Review
  9. Article
  10. Infigratinib, a selective FGFR1-3 tyrosine kinase inhibitor, alters dentoalveolar development at high doses.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Rickets guidance: part II-management.Pediatric nephrology (Berlin, Germany) · 2022
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Iris R HartleyNational Institute of Dental and Craniofacial Research, Bethesda, MD.ORCID 0000-0003-1029-3284
Carole B MillerAscension Saint Agnes Cancer Institute, Baltimore, MD.
Georgios Z PapadakisFoundation for Research and Technology Hellas (FORTH), Heraklion, Greece.
Clemens BergwitzYale University School of Medicine, New Haven, CT.
Jaydira Del RiveroNational Cancer Institute, Bethesda, MD.
Jenny E BlauNational Institute of Diabetes and Digestive and Kidney Disease, Bethesda, MD.
Pablo FlorenzanoPontificia Universidad Catolica de Chile, Santiago, Chile.
Jason A BerglundUniversity of Texas Health Science Center at Houston, Houston, TX.
Jing TassoneNational Institutes of Health, Bethesda, MD.
Kelly L RoszkoNational Institute of Dental and Craniofacial Research, Bethesda, MD.
Susan MoranQED Therapeutics, San Francisco, CA.
Rachel I GafniNational Institute of Dental and Craniofacial Research, Bethesda, MD.
Randi IsaacsNovartis Institutes of Biomedical Research, East Hanover, NJ.
Michael T CollinsNational Institute of Dental and Craniofacial Research, Bethesda, MD mc247k@nih.gov.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Renal Physiology and Phenotyping CoreP30DK079310 · NIDDK · YALE UNIVERSITY · PI ARONSON, PETER S. · 2008 to 2022
$16.8M
Clinical Studies Of Skeletal DiseasesZ01DE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 1995 to 2008
$2.7M
Intramural NIH HHS Z01 DE000649NCATS NIH HHS UL1 TR001863NIDCR NIH HHS Z01 000649 25NIDDK NIH HHS P30 DK079310
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedChondrosarcoma, MesenchymalDisease ProgressionFatal OutcomeFibroblast Growth Factor-23Fibroblast Growth FactorsHumansMaleMolecular Targeted TherapyNeoplasms, Connective TissueOsteomalaciaParaneoplastic SyndromesPhenylurea CompoundsPositron Emission Tomography Computed TomographyPyrimidinesReceptor, Fibroblast Growth Factor, Type 1FGFR1 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsinfigratinibPhenylurea CompoundsPyrimidinesReceptor, Fibroblast Growth Factor, Type 1Receptor Protein-Tyrosine Kinases

Identifiers

PMID32905668
PMCPMC7561341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.