Evidence map›Paper›PMID 32905095›Full record

ReviewExperimental and therapeutic medicine2020

Glucagonoma: From skin lesions to the neuroendocrine component (Review).

Florica Sandru, Mara Carsote, Simona Elena Albu, Ana Valea, Aida Petca, Mihai Cristian Dumitrascu

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Growth Hormone and the Human Hair Follicle.International journal of molecular sciences · 2021
    Review
  6. Review
  7. Review
  8. Neuroendocrine neoplasia and bone (Review).Experimental and therapeutic medicine · 2021
    Review
  9. Review
  10. Anorexia nervosa: COVID-19 pandemic period (Review).Experimental and therapeutic medicine · 2021
    Review
  11. COVID-19-related thyroid conditions (Review).Experimental and therapeutic medicine · 2021
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Florica SandruDepartment of Dermatology, 'Elias' Emergency University Hospital, 125100 Bucharest, Romania.
Mara CarsoteDepartment of Endocrinology,'C.I. Parhon' National Institute of Endocrinology, 011863 Bucharest, Romania.
Simona Elena AlbuDepartment of Gynecology, Emergency University Hospital, 050098 Bucharest, Romania.
Ana ValeaDepartment of Endocrinology, Clinical County Hospital, 400000 Cluj-Napoca, Romania.
Aida PetcaDepartment of Dermatology, 'Elias' Emergency University Hospital, 125100 Bucharest, Romania.
Mihai Cristian DumitrascuDepartment of Gynecology, Emergency University Hospital, 050098 Bucharest, Romania.
Clinical Emergency Hospital Bucharest · ROInstitutul Național de Endocrinologie C.I. Parhon · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucagonoma is a hormonally active rare pancreatic neuroendocrine tumour causing an excess of glucagon. This is a narrative review based on a multidisciplinary approach of the tumour. Typically associated dermatosis is necrolytic migratory erythema (NME) which is most frequently seen at disease onset. Insulin-dependent diabetes mellitus, depression, diarrhoea, deep vein thrombosis are also identified, as parts of so-called 'D' syndrome. Early diagnosis is life saving due to potential aggressive profile and high risk of liver metastasis. NME as paraneoplastic syndrome may be present for months and even years until adequate recognition and therapy; it is remitted after successful pancreatic surgery. Thus the level of practitioners' awareness is essential. If surgery is not curative, debulking techniques may improve the clinical aspects and even the outcome in association with other procedures such as embolization of hepatic metastasis; ablation of radiofrequency type; medical therapy including chemotherapy, targeted therapy with mTOR inhibitors such as everolimus, PRRT (peptide receptor radiotherapy), and somatostatin analogues (including combinations of medical treatments). Increased awareness of the condition involves multidisciplinary practitioners.

Indexed as

glucagonglucagonomanecrolytic migratory erythemaneuroendocrinerushsomatostatin

Identifiers

PMID32905095
PMCPMC7465236
OpenAlexW3039495577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.