Evidence map›Paper›PMID 32904995›Full record

ArticleOpen forum infectious diseases2020

Impact of Infectious Disease Consultation in Patients With Candidemia: A Retrospective Study, Systematic Literature Review, and Meta-analysis.

Takaaki Kobayashi, Alexandre R Marra, Marin L Schweizer, Patrick Ten Eyck, Chaorong Wu, Mohammed Alzunitan, Jorge L Salinas, Marc Siegel, Dimitrios Farmakiotis, Paul G Auwaerter and 2 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

  1. Impact of a pharmacist-led infectious disease support team on candidemia bundle adherence and 28-day mortality: a single-center retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Impact of Biofilm Formation by VaginalJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Review
  5. Validation of the Proposed Definition for Complicated Coagulase-negative Staphylococcal Bacteremia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  6. Article
  7. Article
  8. Carbapenem-resistant Enterobacterales in solid organ transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Takaaki KobayashiDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-4751-6859
Alexandre R MarraDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Marin L SchweizerDivision of Internal Medicine, Department of General Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Patrick Ten EyckInstitute for Clinical and Translational Science, University of Iowa, Iowa City, Iowa, USA.
Chaorong WuInstitute for Clinical and Translational Science, University of Iowa, Iowa City, Iowa, USA.
Mohammed AlzunitanDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Jorge L SalinasDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Marc SiegelDivision of Infectious Diseases, George Washington Medical Faculty Associates, Washington, DC, USA.
Dimitrios FarmakiotisDivision of Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Paul G AuwaerterDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Heather S HealyHardin Library for the Health Sciences, University of Iowa, Iowa City, Iowa, USA.
Daniel J DiekemaDivision of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
University of Iowa · USBrown University · USJohns Hopkins University · USWashington University Medical Center · US

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
NCATS NIH HHS UL1 TR002537
6 · The paper itself

Abstract

backgroundMorbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from

methodsWe conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched 5 databases through February 2020 and performed a meta-analysis of the impact of IDC on the mortality of patients with candidemia.

resultsA total of 151 patients met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%;

conclusionsThis study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with significantly lower mortality and should be considered in all patients with candidemia.

Indexed as

Candida bloodstream infectioncandidemiainfectious disease consultationmortality

Identifiers

PMID32904995
PMCPMC7462368
OpenAlexW3038225140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.