ReviewThe International journal of angiology : official publication of the International College of Angiology, Inc2020
The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia.
Review in The International journal of angiology : official publication of the International College of Angiology, Inc, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Treatment Strategies and Prognostic Outcomes in Acute Limb Ischemia: A Systematic Review and Meta-Analysis Comparing Thrombolytic Therapy and Open Surgical Interventions.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Comparative analysis of surgical and non-surgical wound approaches in diabetic foot ulcer treatment: Meta-analysis and systematic review.International wound journal · 2024Pooled it
- Pooled it
- Clinical magnetic resonance imaging-defined plaque morphology predicts guidewire crossing failure in below-the-knee occlusions in a translational model using amputated lower limbs.Journal of vascular surgery · 2026Article
- Noncontrast magnetic resonance angiography outperforms digital subtraction angiography in detecting hibernating below-the-knee arteries and downgrades Transatlantic Inter-Society Consensus and Global Limb Anatomic Staging System scores in chronic limb-threatening ischemia patients.Journal of vascular surgery · 2026Observational
- Transcatheter Arterialization of the Deep Veins for Chronic Limb-Threatening Ischemia: A Case Series of the Direct Cost Associated With Limb Salvage.Journal of medical cases · 2025Article
- The contemporary natural history of minor amputation among diabetic patients with peripheral arterial disease.Journal of vascular surgery · 2025Article
- Below-Knee Amputations: A Qualitative Social Media Analysis of Perceived Outcomes.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Retrograde endovascular intervention treating chronic limb threatening ischemia: A case report.Radiology case reports · 2025Article
- Developing a Scanning Electron Microscopy Approach to Evaluate Paclitaxel Deposition From Drug Coated Balloons in a Human Cadaveric Peripheral Artery Disease Model.EJVES vascular forum · 2025Article
- Outcomes and Patency of Endovascular Infrapopliteal Reinterventions in Patients With Chronic Limb-Threatening Ischemia.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2024Article
- Major Lower Limb Amputation for Chronic Limb-Threatening Ischemia Is Associated with Poor Long-Term Survival: 4-Year Follow-Up of a Single-Center Experience.Annals of vascular diseases · 2024Article
- Effects of L-Ornithine-L-Aspartate on Angiogenesis and Perfusion in Subacute Hind Limb Ischemia: Preliminary Study.Biomedicines · 2024Article
- Validation of the global limb anatomical staging system in Vietnamese patients treated for chronic limb-threatening ischemia.CVIR endovascular · 2024Article
- Secretome of Hypoxia-Preconditioned Mesenchymal Stem Cells Enhance Angiogenesis in Diabetic Rats with Peripheral Artery Disease.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023Article
- Intralesional Infiltrations of Arteriosclerotic Tissue Cells-Free Filtrate Reproduce Vascular Pathology in Healthy Recipient Rats.International journal of molecular sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Chronic limb-threatening ischemia (CLTI) is a severe form of peripheral artery disease associated with high rates of limb loss. The primary goal of treatment in CLTI is limb salvage via revascularization. Multidisciplinary teams provide improved care for those with CLTI and lead to improved limb salvage rates. Not all patients are candidates for revascularization, and a subset will require major amputation. This article highlights the role of amputations in the management of CLTI, and describes the patients who should be offered primary amputation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.