Evidence map›Paper›PMID 32904463›Full record

ArticleBioMed research international2020

Pharmacokinetic Study of Thirteen Ingredients after the Oral Administration of

Qi Jia, Xuhua Huang, Guangzhe Yao, Wenjuan Ma, Jiayuan Shen, Yanxu Chang, Huizi Ouyang, Jun He

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qi JiaFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Xuhua HuangTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Guangzhe YaoTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Wenjuan MaTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Jiayuan ShenTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Yanxu ChangTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.ORCID https://orcid.org/0000-0002-4198-374X
Huizi OuyangFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.ORCID https://orcid.org/0000-0001-7742-124X
Jun HeTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.ORCID https://orcid.org/0000-0002-3781-9234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rapid and reliable UPLC-MS/MS method was developed and validated for the simultaneous quantification of thirteen bioactive compounds (luteolin, cynaroside, luteolin 7-O-glucuronide, isochlorogenic acid C, chlorogenic acid, cryptochlorogenic acid, apigenin, apigenin 7-glucoside, acacetin, hyperoside, isoquercitrin, tilianin, and hesperidin) in rat plasma. The compounds were separated on an ACQUITY UPLC BEH C

Indexed as

Administration, OralAnimalsChromatography, High Pressure LiquidChrysanthemumDrugs, Chinese HerbalFlavonoidsFlowersGlycosidesMaleMolecular StructurePlant ExtractsRatsRats, Sprague-DawleyTandem Mass SpectrometryDrugs, Chinese HerbalFlavonoidsGlycosidesPlant Extracts

Identifiers

PMID32904463
PMCPMC7456477

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.