Evidence map›Paper›PMID 32904295›Full record

ArticleHeliyon2020

Tramadol enhances PGF

Woo Kim, Kumiko Tanabe, Gen Kuroyanagi, Rie Matsushima-Nishiwaki, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Junko Tachi, Tomoyuki Hioki, Daiki Nakashima and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Woo KimDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Kumiko TanabeDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Gen KuroyanagiDepartment of Rehabilitation Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Rie Matsushima-NishiwakiDepartment of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Kazuhiko FujitaDepartment of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Tetsu KawabataDepartment of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Go SakaiDepartment of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Junko TachiDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Tomoyuki HiokiDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Daiki NakashimaDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Shinobu YamaguchiDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Takanobu OtsukaDepartment of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Haruhiko TokudaDepartment of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Osamu KozawaDepartment of Pharmacology, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Hiroki IidaDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
Gifu University · JPNagoya City University · JPAizawa Hospital · JPNational Center for Geriatrics and Gerontology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoprotegerin (OPG) synthesized by osteoblasts is currently considered a crucial regulator to suppress the formation and function of osteoclasts. We previously showed that the synthesis of OPG is stimulated by prostaglandin F

Indexed as

BiochemistryBoneCell biologyMAP kinaseOsteoblast.OsteoprotegerinPain managementPGF2αPharmaceutical chemistryPharmaceutical sciencePharmacologyTramadolμ-opioid receptor

Identifiers

PMID32904295
PMCPMC7452493
OpenAlexW3080994275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.