Evidence map›Paper›PMID 32904145›Full record

ArticleMedChemComm2019

Introducing nitrogen atoms to amidoalkylindoles: potent and selective cannabinoid type 2 receptor agonists with improved aqueous solubility.

Yue-Yang Ji, Zhi-Long Wang, Fang-Ning Pei, Jun-Jie Shi, Jiao-Jiao Li, Hendra Gunosewoyo, Fan Yang, Jie Tang, Xin Xie, Li-Fang Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Divergent access to 5,6,7-perifused cycles.Nature communications · 2023
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yue-Yang JiShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Zhi-Long WangCAS Key Laboratory of Receptor Research , National Center for Drug Screening , Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 189 Guo Shou Jing Road , Shanghai 201203 , China . Email: xxie@simm.ac.cn.
Fang-Ning PeiShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Jun-Jie ShiShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Jiao-Jiao LiShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Hendra GunosewoyoSchool of Pharmacy and Biomedical Sciences , Faculty of Health Sciences , Curtin University , Bentley , Perth , WA 6102 , Australia.ORCID 0000-0003-3897-1948
Fan YangShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.ORCID 0000-0002-0411-7391
Jie TangShanghai Key Laboratory of Green Chemistry and Chemical Process , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China.
Xin XieCAS Key Laboratory of Receptor Research , National Center for Drug Screening , Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 189 Guo Shou Jing Road , Shanghai 201203 , China . Email: xxie@simm.ac.cn.
Li-Fang YuShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.ORCID 0000-0002-3250-6773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously we identified a series of amidoalkylindoles as potent and selective CB

Identifiers

PMID32904145
PMCPMC7451064

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.