Evidence map›Paper›PMID 32904143›Full record

ReviewInternational cancer conference journal2020

A review with an additional case: amelanotic malignant melanoma at mandibular gingiva.

Revan Birke Koca, Gürkan Ünsal, Merva Soluk Tekkeşin, Gökhan Kasnak, Kaan Orhan, İlknur Özcan, Erhan Fıratlı

Open access · greenAbstract readReview
In one paragraph

Review in International cancer conference journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Revan Birke KocaFaculty of Dentistry, Department of Periodontology, University of Kyrenia, Kyrenia, Cyprus.
Gürkan ÜnsalFaculty of Dentistry, Department of Dentomaxillofacial Radiology, Near East University, Nicosia, Cyprus.ORCID 0000-0001-7832-4249
Merva Soluk TekkeşinInstitute of Oncology, Department of Tumour Pathology, Istanbul University, Istanbul, Turkey.
Gökhan KasnakFaculty of Dentistry, Department of Periodontology, Istanbul University, Istanbul, Turkey.
Kaan OrhanFaculty of Dentistry, Department of Dentomaxillofacial Radiology, Ankara University, Ankara, Turkey.
İlknur ÖzcanFaculty of Dentistry, Department of Dentomaxillofacial Radiology, Istanbul University, Istanbul, Turkey.
Erhan FıratlıFaculty of Dentistry, Department of Periodontology, Istanbul University, Istanbul, Turkey.
Istanbul University · TRAnkara University · TRNear East University · CYUniversity of Kyrenia · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this review with an additional case is to evaluate the clinical, ultrasonographic and histopathological features of a rare case of Amelanotic Malignant Melanoma (AMM) at mandibular gingiva and to compare our case with other published AMMs at mandibular gingiva. A 52-year-old male patient with no systemic diseases was referred to our clinic with a soft tissue lesion at mandibular gingiva. Ultrasonographic examination was performed and a lesion with malignant features was observed. A periapical radiograph was taken to investigate bone destruction and biopsy was planned. Histopathological examination revealed AMM and a literature search was performed to congregate reports which were indexed in PubMed, ScienceDirect, and ResearchGate. Three AMM cases at mandibular gingiva were found. Doppler Ultrasound examination suggested bone destruction and a 1.8 cm × 0.6 cm soft tissue mass with well-defined borders and increased vascularity. Due to its hypervascularity, depth of invasion and destruction at the bone, the lesion was prediagnosed as a malignancy. Lack of melanin pigmentation caused the large immunohistochemical panel study. The tumour cells showed HMB45 and S100 positivity and they were negative with SMA, Desmin, CK1.3, and CK20. Routine ultrasound examination of all soft tissue lesions is very important for assessing features such as vascularity, bone destruction and depth of invasion to detect malignancy. Melanocytic-associated immunohistochemical markers are crucial for AMM diagnosis.

Indexed as

Amelanotic malignant melanomaGingivaHMB45Ultrasound

Identifiers

PMID32904143
PMCPMC7450026
OpenAlexW3042768035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.