Evidence map›Paper›PMID 32904047›Full record

ArticleInternational journal of nanomedicine2020

TiO

Bin Han, Zijie Pei, Lei Shi, Qian Wang, Chen Li, Boyuan Zhang, Xuan Su, Ning Zhang, Lixiao Zhou, Bo Zhao and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. The role of nanocomposites against biofilm infections in humans.Frontiers in cellular and infection microbiology · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Safety assessment of titanium dioxide (E171) as a food additive.EFSA journal. European Food Safety Authority · 2021
    Article
  17. Combined Toxicity of TiONanomaterials (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Bin Han *Department of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Zijie Pei *Department of Pathology, Medical School, China Three Gorge University, Yichang 443002, People's Republic of China.
Lei ShiOccupational Health and Environmental Health, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Qian WangExperimental Center, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Chen LiDepartment of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Boyuan ZhangDepartment of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Xuan SuDepartment of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Ning ZhangDepartment of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Lixiao ZhouDepartment of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Bo ZhaoDepartment of Laboratory Diagnosis, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Yujie NiuOccupational Health and Environmental Health, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.ORCID 0000-0001-7683-3242
Rong ZhangDepartment of Toxicology, Hebei Medical University, Shijiazhuang 050017, Hebei, People's Republic of China.
Hebei Medical University · CNChina Three Gorges University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBecause of the increased production and application of manufactured Nano-TiO

methodsIn the present study,

resultsThe titanium levels of the 1 g/kg group on day-3 and day-7 were significantly increased in liver and kidney as well as significantly decreased in lung compared to day-1. ROS and

conclusionThis work demonstrated that Ti could deposit in lung and enter extra-pulmonary organs of rats and cause oxidative stress, then trigger DNA damage through activating the

Indexed as

DNA DamageAdministration, InhalationAnimalsComet AssayForkhead Box Protein O3KidneyLiverLungMaleMetal NanoparticlesOxidative StressPhosphatidylinositol 3-KinasesRats, Sprague-DawleyReactive Oxygen SpeciesTitaniumForkhead Box Protein O3FOXO3 protein, ratPhosphatidylinositol 3-KinasesReactive Oxygen SpeciesTitaniumtitanium dioxideDNA damageDNA repairGADD45α/ChK2/XRCC1 signaling pathwayNano-TiO2PI3K/AKT/FOXO3a signaling pathway

Identifiers

PMID32904047
PMCPMC7449758
OpenAlexW3057882885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.