Evidence map›Paper›PMID 32903994›Full record

ArticleEuropean thyroid journal2020

Long-Term Clinical Outcome in Familial and Sporadic Papillary Thyroid Carcinoma.

Marco Capezzone, Noemi Fralassi, Chiara Secchi, Silvia Cantara, Lucia Brilli, Tania Pilli, Fabio Maino, Raffaella Forleo, Furio Pacini, Gabriele Cevenini and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in European thyroid journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genetic susceptibility to hereditary non-medullary thyroid cancer.Hereditary cancer in clinical practice · 2022
    Review
  8. Article
  9. DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Review
  10. Familial non-medullary thyroid cancer: a critical review.Journal of endocrinological investigation · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Marco CapezzoneDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Noemi FralassiDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Chiara SecchiDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Silvia CantaraDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Lucia BrilliDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Tania PilliDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Fabio MainoDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Raffaella ForleoDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Furio PaciniDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
Gabriele CeveniniDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Alessandra CartocciDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.
Maria Grazia CastagnaDepartment of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe definition and the behaviour of familial papillary thyroid cancer (FPTC) compared to the sporadic form (SPTC) are still debated. Some authors believe that only families with 3 or more affected members represent an actual example of familial diseases.

objectivesThe objective of the study was to analyse the clinicopathological features and the outcome of sporadic and familial PTC patients also according to the number of affected members.

methodsAmong 731 patients, we identified 101 (13.8%) with familial diseases, 79 with 2 affected members (FPTC-2) and 22 with 3 or more affected members (FPTC-3) followed for a mean period of 10 years.

resultsFPTC patients had more frequently bilateral tumour (

conclusionsOur results suggest that, although the clinicopathological features of FPTC may be more aggressive, the long-term outcome is similar between FPTC and SPTC. A possible explanation is that PTC has a favourable prognosis, even when clinical presentation is more aggressive.

Indexed as

Familial papillary thyroid cancerOutcomePrognosisRecurrencesSporadic papillary thyroid cancer

Identifiers

PMID32903994
PMCPMC7445652
OpenAlexW3021920166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.