Evidence map›Paper›PMID 32903971›Full record

ArticleEuropean thyroid journal2020

European Thyroid Association Survey on Use of Minimally Invasive Techniques for Thyroid Nodules.

Laszlo Hegedüs, Andrea Frasoldati, Roberto Negro, Enrico Papini

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in European thyroid journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07237373 (Percutaneous Thermo-ablation for the Treatment of Benign Thyroid Nodules), which is not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07237373 recruitingnot on this mapstarted 2026, after this paper: background citation

Percutaneous Thermo-ablation for the Treatment of Benign Thyroid Nodules: a Prospective Multicentric Study

Typeobservational_patient_registrySponsorUniversity Hospital, GhentRan2026 to 2031Enrolled100ConditionsBenign Thyroid NoduleArmsPercutaneous radiofrequency ablation
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  20. Nonsurgical Management of Thyroid Nodules: The Role of Ablative Therapies.The Journal of clinical endocrinology and metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Laszlo HegedüsDepartment of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark.
Andrea FrasoldatiDivision of Endocrinology, Arcispedale S. Maria Nuova, Reggio Emilia, Italy.
Roberto NegroDivision of Endocrinology, "V. Fazzi" Hospital, Lecce, Italy.
Enrico PapiniDivision of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy.
Odense University Hospital · DKOspedale Regina Apostolorum · ITOspedale Vito Fazzi · ITSanta Maria Nuova Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveImage-guided interventional ultrasound (US) techniques represent diagnostic and therapeutic tools for non-surgical management of thyroid nodular disease. We sought to investigate the attitude of European Thyroid Association (ETA) members towards the use of minimally invasive techniques (MIT) in diagnosis/therapy of symptomatic nodular goitre.

methodsETA members were invited to participate in an online survey investigating the use of MIT in benign and malignant thyroid nodular disease. Of 865 invited members, 221 (25.5%) completed the survey. The respondents were from 40 countries; 139 (74.7%) were from European countries.

resultsRespondents personally performed thyroid US (91.6%), Fine needle aspiration (FNA; 75.3%), ethanol ablation (EA; 22.1%), core needle biopsy (CNB; 11%) and thermal treatments (4.8%). When skills and/or technology were unavailable, only 13.4% referred patients "often" or "always" to other centres with specific expertise in this field. Surgery was the preferred first option in patients with recurrent cysts, 4.0 cm benign nodules, local (radioiodine-avid or non-avid) lymph node metastases, or papillary cancers <1.0 cm. For autonomously functioning nodules radioactive iodine treatment was the preferred choice, followed by surgery. Thermal ablation (TA) was the preferred option only for a 4 cm benign nodule in old patients with comorbidities.

conclusionsUS, US-guided FNA and surgery were available to nearly all respondents, while MIT was not. CNB and EA were employed only by about 1/3 of the respondents and TA procedures were available and personally performed only by a minority. For most thyroid lesions, surgery was the preferred option versus thermal therapies. The ETA needs to develop guidelines and establish teaching to overcome geographic inequality and promote the use of MIT as a valid therapy option in appropriate cases.

Indexed as

Ethanol ablationEuropean thyroid associationLaser ablationQuestionnaireRadiofrequency ablationThermal ablationThyroid cancerThyroid cystsThyroid nodules

Identifiers

PMID32903971
PMCPMC7445736
OpenAlexW3013784844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.