Evidence map›Paper›PMID 32903778›Full record

ArticleFrontiers in immunology2020

Pre-transplant Thymic Function Predicts Is Associated With Patient Death After Kidney Transplantation.

Cécile Courivaud, Jamal Bamoulid, Thomas Crepin, Emilie Gaiffe, Caroline Laheurte, Philippe Saas, Didier Ducloux

Abstract readMulticenter Study
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Exhaustion of CD8Frontiers in immunology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Exhaustion of CD8Frontiers in immunology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cécile CourivaudInserm, UMR1098, Federation Hospitalo-Universitaire INCREASE, Besançon, France.
Jamal BamoulidInserm, UMR1098, Federation Hospitalo-Universitaire INCREASE, Besançon, France.
Thomas CrepinInserm, UMR1098, Federation Hospitalo-Universitaire INCREASE, Besançon, France.
Emilie GaiffeCHU Besançon, Department of Nephrology, Dialysis, and Renal Transplantation, Besançon, France.
Caroline LaheurteInserm, UMR1098, Federation Hospitalo-Universitaire INCREASE, Besançon, France.
Philippe SaasInserm, UMR1098, Federation Hospitalo-Universitaire INCREASE, Besançon, France.
Didier DuclouxInserm, UMR1098, Federation Hospitalo-Universitaire INCREASE, Besançon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accelerated thymic involution is a main feature of end-stage renal disease (ESRD)-associated immune senescence. Recent evidences suggest that ESRD-associated immune senescence is associated with adverse outcomes in dialysis patients. However, no study focused on the association between pre-transplant thymic function and patient survival after transplantation. We conducted a prospective, multicenter study to assess whether pre-transplant thymic function measured by recent thymic emigrants (RTE) may predict death after first kidney transplantation. Results were tested in a validation cohort. Nine hundred and sixty-seven incident kidney transplant recipients were included in the prospective study. Mean follow up was 5.1 + 2.9 years. Eighty two patients (8.5%) died during follow up. Lower RTE levels were associated with a higher risk of death (2.53; 95%CI, 1.54-4.39 for each decrease of 1 log in RTE;

Indexed as

ImmunosenescenceAdultAgedFemaleFranceHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedPhenotypeProspective StudiesRetrospective StudiesRisk AssessmentRisk FactorsThymus Glandcancerdeathimmune senescencekidney transplantationthymus

Identifiers

PMID32903778
PMCPMC7438875

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.