Evidence map›Paper›PMID 32903712›Full record

ArticleFrontiers in neuroscience2020

Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson's Disease.

Wiebke Hermann, Henning Schmitz-Peiffer, Elisabeth Kasper, Mareike Fauser, Christiana Franke, Miriam Wienecke, Karolin Otto, Matthias Löhle, Moritz D Brandt, Heinz Reichmann and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Management of Sleep Disturbances in Parkinson's Disease.Journal of Parkinson's disease · 2022
    Review
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Wiebke HermannDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Henning Schmitz-PeifferDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Elisabeth KasperDepartment of Neurology, University of Rostock, Rostock, Germany.
Mareike FauserDepartment of Neurology, University of Rostock, Rostock, Germany.
Christiana FrankeDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Miriam WieneckeDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Karolin OttoDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Matthias LöhleDepartment of Neurology, University of Rostock, Rostock, Germany.
Moritz D BrandtDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Heinz ReichmannDepartment of Neurology, Technische Universität Dresden, Dresden, Germany.
Alexander StorchDepartment of Neurology, University of Rostock, Rostock, Germany.
TU Dresden · DEUniversity of Rostock · DEGerman Center for Neurodegenerative Diseases · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep disturbances and impairment of cognitive function are among the most frequent non-motor symptoms in Parkinson's disease (PD) with negative implications on quality of life of patients and caregivers. Despite the fact that sleep disturbances are a major issue in PD patients, only limited data are available regarding interactions of sleep disturbances and cognitive performance.

objectiveThis

methodsTwenty-six PD patients with sleep disturbances were evaluated thoroughly including assessments of patients' subjective and objective sleep quality by interview, questionnaires, and polysomnography (PSG). Cognitive performance was assessed by Parkinson Neuropsychometric Dementia Assessment (PANDA) and Test of Attentional Performance (TAP), and associations of sleep and cognitive function were evaluated.

resultsWe did not detect differences in cognitive performance between patients with and without rapid eye movement (REM) sleep behavior disorder (RBD). Instead, cognitive impairment, particularly affecting cognitive domains attention, executive function/working memory, and semantic memory, was associated with impaired PSG-measured sleep quality (e.g., sleep efficiency) and sleep disordered breathing (SDB) (Apnea-Hypopnea Index > 5/h). Global cognitive performance was decreased in patients with SDB (PANDA score 23.2 ± 3.5 vs. 26.9 ± 2.2,

conclusionSleep apnea and other sleep disturbances impair cognitive performance in PD and should be evaluated in routine care, and treatment options such as continuous airway pressure therapy should be considered.

Indexed as

cognitioncognitive performanceParkinson’s diseasesleep apneasleep disordered breathingsleep disorders

Identifiers

PMID32903712
PMCPMC7438827
OpenAlexW3047322773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.