Evidence map›Paper›PMID 32903492›Full record

ReviewFrontiers in medicine2020

Pulmonary and Extra-Pulmonary Clinical Manifestations of COVID-19.

Kemmian D Johnson, Christen Harris, John K Cain, Cicily Hummer, Hemant Goyal, Abhilash Perisetti

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 6 pooled it
3.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 6 syntheses or guidelines pooled it, 175 citations in OpenAlex.

  1. Pooled it
  2. COVID-19-associated Brugada pattern electrocardiogram: Systematic review of case reports.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Pooled it
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  7. Review
  8. Article
  9. Marked Sinus Bradycardia in a COVID-19 Patient.Case reports in cardiology · 2025
    Article
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Kemmian D JohnsonDepartment of Internal Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Christen HarrisDepartment of Internal Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
John K CainDepartment of Nurse Anesthesia, Texas Christian University, Fort Worth, TX, United States.
Cicily HummerCollege of Medicine, Rocky Vista University College of Osteopathic Medicine, Parker, CO, United States.
Hemant GoyalDepartment of Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, PA, United States.
Abhilash PerisettiDepartment of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Louisiana State University Health Sciences Center New Orleans · USRocky Vista University · USTexas Christian University · USThe Wright Center for Graduate Medical Education · USUniversity of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been recently identified as the culprit of the highly infectious, outbreak named coronavirus disease 2019 (COVID-19) in China. Now declared a public health emergency, this pandemic is present in more than 200 countries with over 14 million cases and 600,000 deaths as of July 18, 2020. Primarily transmitted through the respiratory tract, the most common clinical presentations of symptomatic individuals infected with SARS-CoV-2 include fever, dyspnea, cough, fatigue, and sore throat. In advanced cases, patients may rapidly develop respiratory failure with acute respiratory distress syndrome, and even progress to death. While it is known that COVID-19 manifests similarly to the 2003 Severe Acute Respiratory Syndrome (SARS) and the 2012 Middle East Respiratory Syndrome (MERS), primarily affecting the pulmonary system, the impact of the disease extends far beyond the respiratory system and affects other organs of the body. The literature regarding the extrapulmonary manifestations (cardiovascular, renal, hepatic, gastrointestinal, ocular, dermatologic, and neurological) of COVID-19 is scant. Herein, we provide a comprehensive review of the organ-specific clinical manifestations of COVID-19, to increase awareness about the various organs affected by SARS-CoV-2 and to provide a brief insight into the similarities and differences in the clinical manifestations of COVID-19 and the earlier SARS and MERS.

Indexed as

coronavirus 2019COVID-19MERS-CoVpneumoniaSARS-CoV-1SARS-CoV-2

Identifiers

PMID32903492
PMCPMC7438449
OpenAlexW3049010972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.