Evidence map›Paper›PMID 32903484›Full record

ArticleFrontiers in immunology2020

MAp34 Regulates the Non-specific Cell Immunity of Monocytes/Macrophages and Inhibits the Lectin Pathway of Complement Activation in a Teleost Fish.

Liangliang Mu, Xiaoxue Yin, Hairong Wu, Kailiang Han, Zheng Guo, Jianmin Ye

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liangliang MuGuangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, Institute of Modern Aquaculture Science and Engineering, South China Normal University, Guangzhou, China.
Xiaoxue YinGuangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, Institute of Modern Aquaculture Science and Engineering, South China Normal University, Guangzhou, China.
Hairong WuGuangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, Institute of Modern Aquaculture Science and Engineering, South China Normal University, Guangzhou, China.
Kailiang HanGuangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, Institute of Modern Aquaculture Science and Engineering, South China Normal University, Guangzhou, China.
Zheng GuoGuangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, Institute of Modern Aquaculture Science and Engineering, South China Normal University, Guangzhou, China.
Jianmin YeGuangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, Institute of Modern Aquaculture Science and Engineering, South China Normal University, Guangzhou, China.
South China Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lectin pathway of the complement system is one of the main components of innate immunity, which plays a pivotal role in the defense against infectious microorganisms and maintains immune homeostasis. However, its control mechanisms remain unclear in teleost fish. In this study, we described the identification and functional characterization of a mannose-binding lectin associated protein MAp34 (OnMAp34) from Nile tilapia (

Indexed as

Complement Pathway, Mannose-Binding LectinImmunity, CellularImmunity, InnateAnimalsCells, CulturedCichlidsFemaleFish ProteinsGene Expression RegulationMacrophagesMannose-Binding LectinMice, Inbred BALB CMonocytesPhagocytosisSignal TransductionFish ProteinsMannose-Binding Lectincompetitive inhibitionlectin pathwayMAp34non-specific cell immunityOreochromis niloticus

Identifiers

PMID32903484
PMCPMC7435015
OpenAlexW3048775174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.