Evidence map›Paper›PMID 32903459›Full record

ReviewFrontiers in molecular biosciences2020

Type IV Coupling Proteins as Potential Targets to Control the Dissemination of Antibiotic Resistance.

Itxaso Álvarez-Rodríguez, Lide Arana, Begoña Ugarte-Uribe, Elena Gómez-Rubio, Sonsoles Martín-Santamaría, Carlos Garbisu, Itziar Alkorta

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

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  12. One Earth: The Equilibrium between the Human and the Bacterial Worlds.International journal of molecular sciences · 2023
    Review
  13. Development of a high-throughput platform to measure plasmid transfer frequency.Frontiers in cellular and infection microbiology · 2023
    Article
  14. Article
  15. Genomic Insights ofFrontiers in microbiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Itxaso Álvarez-RodríguezDepartment of Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain.
Lide AranaDepartment of Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain.
Begoña Ugarte-UribeDepartment of Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain.
Elena Gómez-RubioDepartment of Structural and Chemical Biology, Centro de Investigaciones Biológicas Margarita Salas, CIB-CSIC, Madrid, Spain.
Sonsoles Martín-SantamaríaDepartment of Structural and Chemical Biology, Centro de Investigaciones Biológicas Margarita Salas, CIB-CSIC, Madrid, Spain.
Carlos GarbisuDepartment of Conservation of Natural Resources, Soil Microbial Ecology Group, NEIKER - Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), Parque Cient fico y Tecnológico de Bizkaia, Derio, Spain.
Itziar AlkortaDepartment of Biochemistry and Molecular Biology, University of the Basque Country, Leioa, Spain.
University of the Basque Country · ESCentro de Investigaciones Biológicas Margarita Salas · ESEuskadiko Parke Teknologikoa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase of infections caused by multidrug-resistant bacteria, together with the loss of effectiveness of currently available antibiotics, represents one of the most serious threats to public health worldwide. The loss of human lives and the economic costs associated to the problem of the dissemination of antibiotic resistance require immediate action. Bacteria, known by their great genetic plasticity, are capable not only of mutating their genes to adapt to disturbances and environmental changes but also of acquiring new genes that allow them to survive in hostile environments, such as in the presence of antibiotics. One of the major mechanisms responsible for the horizontal acquisition of new genes (

Indexed as

antibiotic resistancebacterial conjugationcoupling proteinsdrug discoverynovel conjugation inhibitors

Identifiers

PMID32903459
PMCPMC7434980
OpenAlexW3048693617

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.