Evidence map›Paper›PMID 32903413›Full record

ArticleFrontiers in nutrition2020

Bacteria Remediate the Effects of Food Additives on Intestinal Function in an

Mridu Malik, Sanjeena Subedi, Cláudia N H Marques, Gretchen J Mahler

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pharmacological insights intoFrontiers in pharmacology · 2025
    Pooled it
  2. Article
  3. Surface layer proteins fromTissue barriers · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mridu MalikDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, United States.
Sanjeena SubediDepartment of Mathematical Sciences, Binghamton University, Binghamton, NY, United States.
Cláudia N H MarquesBinghamton Biofilm Research Center, Binghamton University, Binghamton, NY, United States.
Gretchen J MahlerDepartment of Biomedical Engineering, Binghamton University, Binghamton, NY, United States.
Binghamton University · US

Funding

Engineering a Small Intestinal Microbiome to Evaluate Food Additive ExposureR01ES028788 · NIEHS · STATE UNIVERSITY OF NY,BINGHAMTON · PI MAHLER, GRETCHEN, MARQUES, CLAUDIA N.H. · 2018 to 2022
$1.5M
NIEHS NIH HHS R01 ES028788
6 · The paper itself

Abstract

As the site of nutrient absorption, the small intestine is continuously exposed to preservatives and additives present in consumed food. While the effects of diet on the lower gastrointestinal tract are widely studied, the effects of food additives on the small intestinal epithelium and microbiota are less clearly understood. The goal of this work was to develop and establish a physiologically relevant model of the upper gastrointestinal tract to study the complex interactions between food additives, individual bacterial species, and intestinal function. To achieve this, an

Indexed as

brush border enzymeCaco-2food additivesHT29-MTXin vitro digestionmicrobiotananoparticles

Identifiers

PMID32903413
PMCPMC7434930
OpenAlexW3048958427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.