Evidence map›Paper›PMID 32903409›Full record

ArticleFrontiers in neurology2020

Slow Titration of Cannabidiol Add-On in Drug-Resistant Epilepsies Can Improve Safety With Maintained Efficacy in an Open-Label Study.

Gianluca D'Onofrio, Mathieu Kuchenbuch, Caroline Hachon-Le Camus, Béatrice Desnous, Véronique Staath, Sylvia Napuri, Dorothée Ville, Jean-Michel Pedespan, Anne Lépine, Claude Cances and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Gianluca D'OnofrioDepartment of Pediatric Neurology, Reference Centre for Rare Epilepsies, Hôpital Necker-Enfants Malades, APHP, Paris, France.
Mathieu KuchenbuchDepartment of Pediatric Neurology, Reference Centre for Rare Epilepsies, Hôpital Necker-Enfants Malades, APHP, Paris, France.
Caroline Hachon-Le CamusDepartment of Pediatric Neurology, Hôpital des Enfants, Toulouse University Hospital, Toulouse, France.
Béatrice DesnousAP-HM, Pediatric Neurology Department, Timone Children Hospital, Marseille, France.
Véronique StaathDepartment of Pediatric Neurology, Strasbourg University Hospital, Hopital de Hautepierre, Strasbourg, France.
Sylvia NapuriDepartment of Pediatrics, Rennes University Hospital, University Rennes, Rennes, France.
Dorothée VilleDepartment of Pediatric Neurology, CNRS UMR 5304, Bron, France.
Jean-Michel PedespanDepartment of Pediatrics, Pellegrin University Hospital, Bordeaux, France.
Anne LépineAP-HM, Pediatric Neurology Department, Timone Children Hospital, Marseille, France.
Claude CancesDepartment of Pediatric Neurology, Hôpital des Enfants, Toulouse University Hospital, Toulouse, France.
Anne de Saint-MartinDepartment of Pediatric Neurology, Strasbourg University Hospital, Hopital de Hautepierre, Strasbourg, France.
Théo TengDepartment of Pediatric Neurology, Reference Centre for Rare Epilepsies, Hôpital Necker-Enfants Malades, APHP, Paris, France.
Nicole ChemalyDepartment of Pediatric Neurology, Reference Centre for Rare Epilepsies, Hôpital Necker-Enfants Malades, APHP, Paris, France.
Mathieu MilhAP-HM, Pediatric Neurology Department, Timone Children Hospital, Marseille, France.
Nathalie VilleneuveAP-HM, Pediatric Neurology Department, Timone Children Hospital, Marseille, France.
Rima NabboutDepartment of Pediatric Neurology, Reference Centre for Rare Epilepsies, Hôpital Necker-Enfants Malades, APHP, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRHôpital des Enfants · FRHôpital d'Hautepierre · FRUniversité Paris Cité · FRCentre Hospitalier Universitaire de Rennes · FRCentre National de la Recherche Scientifique · FRHôpital Pellegrin · FRUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adverse eventsDravetdrug resistantLennox-Gastautliver functiontolerability

Identifiers

PMID32903409
PMCPMC7434926
OpenAlexW3042990227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.