Evidence map›Paper›PMID 32903402›Full record

ArticleFrontiers in immunology2020

Protease-Activated Receptor-2 Regulates Neuro-Epidermal Communication in Atopic Dermatitis.

Timo Buhl, Akihiko Ikoma, Cordula Kempkes, Ferda Cevikbas, Mathias Sulk, Joerg Buddenkotte, Tasuku Akiyama, Debbie Crumrine, Eric Camerer, Earl Carstens and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Neutrophils in Atopic Dermatitis.Clinical reviews in allergy & immunology · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Challenges and Future Trends in Atopic Dermatitis.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

Timo BuhlDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Akihiko IkomaDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Cordula KempkesDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Ferda CevikbasDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Mathias SulkDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Joerg BuddenkotteDepartment of Dermatology and Venerology, Hamad Medical Corporation, Doha, Qatar.
Tasuku AkiyamaDepartment of Dermatology, Anatomy and Cell Biology, Temple Itch Center, Temple University, Philadelphia, PA, United States.
Debbie CrumrineDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Eric CamererINSERM U970, Paris Cardiovascular Research Centre, Paris, France.
Earl CarstensDepartment of Neurobiology, Physiology and Behavior, University of California, Davis, Davis, CA, United States.
Michael P SchönDepartment of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.
Peter EliasDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
Shaun R CoughlinCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, United States.
Martin SteinhoffDepartment of Dermatology and Surgery, University of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · USUniversitätsmedizin Göttingen · DEUniversity of California, Davis · USHamad Medical Corporation · QAInserm · FRUniversity College Dublin · IE

Funding

Spinal mechanisms of itchR01AR057194 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CARSTENS, EARL E · 2009 to 2019
$3.4M
Role of NK-1 receptors in descending modulation and ascending transmission of itchR01AR076434 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CARSTENS, EARL E · 2020 to 2024
$1.7M
NIAMS NIH HHS R01 AR057194NIAMS NIH HHS R01 AR076434
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnimals, Genetically ModifiedCalcium SignalingDermatitis, AtopicDisease Models, AnimalEndothelin-1EpidermisGanglia, SpinalKeratinocytesNerve Growth FactorPruritusPyroglyphidaeReceptor, PAR-2Endothelin-1F2rl1 protein, mouseNerve Growth FactorReceptor, PAR-2atopic dermatitisdorsal root ganglionendothelinhouse dust miteneuro-immunologyPAR2protease-activated receptor-2

Identifiers

PMID32903402
PMCPMC7435019
OpenAlexW3048733953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.