Evidence map›Paper›PMID 32903342›Full record

ReviewBMC biomedical engineering2020

Tourniquet-induced nerve compression injuries are caused by high pressure levels and gradients - a review of the evidence to guide safe surgical, pre-hospital and blood flow restriction usage.

Bassam A Masri, Andrew Eisen, Clive P Duncan, James A McEwen

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in BMC biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06781021 (The Effect of Tranexamic Acid Vs Torniquet on Visual Clarity in Knee Arthroscopic Anterior Cruciate Ligament), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06781021 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

The Effect of Tranexamic Acid Vs Torniquet on Visual Clarity in Knee Arthroscopic Anterior Cruciate Ligament (ACL) Reconstruction

TypeinterventionalSponsorThe University of The West IndiesRan2024 to 2026Enrolled60ConditionsACL TearsArmsTourniquet, TXA
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Blood Flow Restriction Training in Hemodialysis Patients: Clinical Benefits, Challenges, and Future Perspectives.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Sciatic Nerve Palsy Caused by Tourniquet Use After Pediatric Knee Meniscal Surgery.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bassam A MasriDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, 207-1099 West 8th Avenue, Vancouver, BC V6H 1C3 Canada.
Andrew EisenDivision of Neurology, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Clive P DuncanDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, 207-1099 West 8th Avenue, Vancouver, BC V6H 1C3 Canada.
James A McEwenDepartment of Orthopaedics, Faculty of Medicine, University of British Columbia, 207-1099 West 8th Avenue, Vancouver, BC V6H 1C3 Canada.ORCID https://orcid.org/0000-0002-1459-1046
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tourniquets in orthopaedic surgery safely provide blood free surgical fields, but their use is not without risk. Tourniquets can result in temporary or permanent injury to underlying nerves, muscles, blood vessels and soft tissues. Advances in safety, accuracy and reliability of surgical tourniquet systems have reduced nerve-related injuries by reducing pressure levels and pressure gradients, but that may have resulted in reduced awareness of potential injury mechanisms. Short-term use of pre-hospital tourniquets is effective in preventing life-threatening blood loss, but a better understanding of the differences between tourniquets designed for pre-hospital vs surgical use will provide a framework around which to develop guidelines for admitting to hospital individuals with pre-applied tourniquets. Recent evidence supports the application of tourniquets for blood flow restriction (BFR) therapy to reduce muscular atrophy, increase muscle strength, and stimulate bone growth. BFR therapy when appropriately prescribed can augment a surgeon's treatment plan, improving patient outcomes and reducing recovery time. Key risks, hazards, and mechanisms of injury for surgical, BFR therapy, and pre-hospital tourniquet use are identified, and a description is given of how advances in personalized tourniquet systems have reduced tourniquet-related injuries in these broader settings, increasing patient safety and how these advances are improving treatment outcomes.

Indexed as

CompressionInjuriesNervePersonalizationPressureSafetyTourniquet

Identifiers

PMID32903342
PMCPMC7422508
OpenAlexW3030297108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.