Evidence map›Paper›PMID 32903033›Full record

ArticleCirculation. Arrhythmia and electrophysiology2020

Prospective STAR-Guided Ablation in Persistent Atrial Fibrillation Using Sequential Mapping With Multipolar Catheters.

Shohreh Honarbakhsh, Richard J Schilling, Malcolm Finlay, Emily Keating, Ross J Hunter

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02950844 (Identification, Electro-mechanical Characterisation and Ablation of Driver Regions in Persistent Atrial Fibrillation), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02950844 nacompletednot on this map

Identification, Electro-mechanical Characterisation and Ablation of Driver Regions in Persistent Atrial Fibrillation (STAR MAPPING)

TypeinterventionalSponsorBarts & The London NHS TrustRan2016 to 2019Enrolled60ConditionsAtrial FibrillationArmsNovel mapping algorithm
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Multi-centre, prospective randomized comparison of three different substrate ablation strategies for persistent atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Advances in basic and translational research in atrial fibrillation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  7. Rotor mechanism and its mapping in atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
  8. Article
  9. [New mapping tools for catheter ablation of atrial fibrillation].Herzschrittmachertherapie & Elektrophysiologie · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shohreh HonarbakhshBarts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Richard J SchillingBarts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Malcolm FinlayBarts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Emily KeatingBarts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Ross J HunterBarts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Barts Health NHS Trust · GB

Funding

British Heart Foundation PG/16/10/32016
6 · The paper itself

Abstract

backgroundA novel stochastic trajectory analysis of ranked signals (STAR) mapping approach to guide atrial fibrillation (AF) ablation using basket catheters recently showed high rates of AF termination and subsequent freedom from AF.

methodsThis study aimed to determine whether STAR mapping using sequential recordings from conventional pulmonary vein mapping catheters could achieve similar results. Patients with persistent AF<2 years were included. Following pulmonary vein isolation AF drivers (AFDs) were identified on sequential STAR maps created with PentaRay, IntellaMap Orion, or Advisor HD Grid catheters. Patients had a minimum of 10 multipolar recordings of 30 seconds each. These were processed in real-time and AFDs were targeted with ablation. An ablation response was defined as AF termination or cycle length slowing ≥30 ms.

resultsThirty patients were included (62.4±7.8 years old, AF duration 14.1±4.3 months) of which 3 had AF terminated on pulmonary vein isolation, leaving 27 patients that underwent STAR-guided AFD ablation. Eighty-three potential AFDs were identified (3.1±1.1 per patient) of which 70 were targeted with ablation (2.6±1.2 per patient). An ablation response was seen at 54 AFDs (77.1% of AFDs; 21 AF termination and 33 cycle length slowing) and occurred in all 27 patients. No complications occurred. At 17.3±10.1 months, 22 out of 27 (81.5%) patients undergoing STAR-guided ablation were free from AF/atrial tachycardia off antiarrhythmic drugs.

conclusionsSTAR-guided AFD ablation through sequential mapping with a multipolar catheter effectively achieved an ablation response in all patients. AF terminated in a majority of patients, with a high freedom from AF/atrial tachycardia off antiarrhythmic drugs at long-term follow-up. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02950844.

Indexed as

Cardiac CathetersHeart RateAction PotentialsAgedAtrial FibrillationCatheter AblationDisease-Free SurvivalElectrophysiologic Techniques, CardiacFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsPredictive Value of TestsProspective Studiesatrial fibrillationcatheter ablationcoronary sinuspulmonary veintachycardia

Identifiers

PMID32903033
PMCPMC7566307
OpenAlexW3083854322

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.