Evidence map›Paper›PMID 32902728›Full record

ArticleWorld journal of urology2021

Informative value of histological assessment of tissue acquired during aquablation of the prostate.

Gautier Müllhaupt, Annette Enzler-Tschudy, Katarina Horg, Lukas Bubendorf, Manolis Pratsinis, Hans-Peter Schmid, Dominik Abt

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Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gautier Müllhaupt *Department of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland. gautier.muellhaupt@kssg.ch.ORCID http://orcid.org/0000-0002-5725-5608
Annette Enzler-Tschudy *Department of Pathology, St. Gallen Cantonal Hospital, St. Gallen, Switzerland.
Katarina HorgDepartment of Pathology, St. Gallen Cantonal Hospital, St. Gallen, Switzerland.
Lukas BubendorfInstitute of Medical Genetics and Pathology, University Hospital of Basel, Basel, Switzerland.
Manolis PratsinisDepartment of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.
Hans-Peter SchmidDepartment of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.
Dominik AbtDepartment of Urology, St. Gallen Cantonal Hospital, Klinik für Urologie, Rorschacherstrasse 95, 9007, St. Gallen, Switzerland.
Kantonsspital St. Gallen · CHUniversity Hospital of Basel · CHUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the histological validity of the tissue acquired during aquablation of the prostate. PATIENTS AND

methodsProstatic tissue of 12 patients that consecutively underwent aquablation for benign prostatic enlargement was systematically examined. Histological examination was performed by two experienced uropathologists using a digital slide scanner and slide viewer software (Pannoramic 250 and Case Viewer 2.3, 3D Histech, Hungary). The surface areas of the assessable glands were examined and set in relation to the total surface area of the material available for histology and to the patient's total prostate volume. Examinations were performed analogously in ten consecutive patients undergoing transurethral resection of the prostate (TURP) to facilitate interpretation of the results. Data were analyzed using descriptive statistics.

resultsA median of 4.06% (range 1.43-7.5%) of the preoperative total prostate volume (median 64.5 ml (range 40-80 ml)) was obtained for histological examination by aquablation. Due to severe mechanical destruction and fragmentation, only a proportion of 0.43% (0.06-1.79%) of this tissue represented histologically assessable glands. Therefore, roughly 0.017% of the total prostatic volume was available for a reliable histological examination. In comparison, 32.5% (6.67-37.5%) of the total prostate volume was removed by TURP and 22.86% (7.45-40.57%) of this tissue represented informative prostatic glands, corresponding to 7.43% of the total prostate volume.

conclusionHistological significance of the tissue obtained by aquablation of the prostate is very limited. Costs and effort of the histological examination must, therefore, be weighed critically against the limited informative value.

Indexed as

Ablation TechniquesHumansMaleProstatectomyProstatic HyperplasiaReproducibility of ResultsWaterWaterAquaBeamAquablationBenign prostatic hyperplasiaHistologyProstateprostate tissue

Identifiers

PMID32902728
OpenAlexW3084823736

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.