Evidence map›Paper›PMID 32902659›Full record

ArticleAbdominal radiology (New York)2020

PI-RADS version 2.1 scoring system is superior in detecting transition zone prostate cancer: a diagnostic study.

Zhibing Wang, Wenlu Zhao, Junkang Shen, Zhen Jiang, Shuo Yang, Shuangxiu Tan, Yueyue Zhang

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Article in Abdominal radiology (New York), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

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6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zhibing Wang *Department of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Wenlu Zhao *Department of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Junkang ShenDepartment of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China. shenjunkang@suda.edu.cn.
Zhen JiangDepartment of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Shuo YangDepartment of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Shuangxiu TanDepartment of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yueyue ZhangDepartment of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe studies comparing the versions 2 vs. 2.1 of the Prostate Imaging Reporting and Data System (PI-RADS) are rare. This study aimed to evaluate whether PI-RADS version 2.1 is superior in detecting transition zone prostate cancer in comparison with PI-RADS version 2.

methodsThis was a diagnostic study of patients with prostate diseases who visited the Urology Department of The Second Affiliated Hospital of Soochow University and underwent a magnetic resonance imaging (MRI) examination between 03-01-2016 and 10-31-2018. The images originally analyzed using PI-RADS version 2 were retrospectively re-analyzed and scored in 2019 according to the updated PI-RADS version 2.1. The kappa and receiver operating characteristic (ROC) curves were used.

resultsFor Reader 1, compared with PI-RADS version 2, version 2.1 had higher sensitivity (85% vs. 79%, P = 0.03), lower specificity (65% vs. 83%, P < 0.001), and lower area under the curve (AUC) (0.749 vs. 0.809, P < 0.001). For Reader 2 (first attempt), compared with PI-RADS version 2, version 2.1 had lower specificity (67% vs. 91%, P < 0.001) and lower AUC (0.702 vs. 0.844, P < 0.001). For Reader 2 (second attempt), compared with PI-RADS version 2, version 2.1 had higher sensitivity (88% vs. 78%, P < 0.001) and lower specificity (77% vs. 91%, P < 0.001). The kappa between the two attempts for Reader 2 was 0.321.

conclusionThese results suggest that PI-RADS version 2.1 might improve the detection of prostate cancers in the transition zone compared with PI-RADS version 2 but that it might results in higher numbers of biopsies because of lower specificity.

Indexed as

Magnetic Resonance ImagingProstatic NeoplasmsBiopsyHumansMaleRetrospective StudiesDiagnostic valueMagnetic resonance imagingProstate cancerTransition zone

Identifiers

PMID32902659

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