Evidence map›Paper›PMID 32902391›Full record

ArticleJMIR diabetes2020

Intervention Enhancement Strategies Among Adults With Type 2 Diabetes in a Very Low-Carbohydrate Web-Based Program: Evaluating the Impact With a Randomized Trial.

Laura R Saslow, Judith Tedlie Moskowitz, Ashley E Mason, Jennifer Daubenmier, Bradley Liestenfeltz, Amanda L Missel, Hovig Bayandorian, James E Aikens, Sarah Kim, Frederick M Hecht

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR diabetes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02676648 (Randomized Trial of Web-Delivered Interventions for Blood Sugar Control for Individuals With Type 2 Diabetes), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02676648 nacompletednot on this map

Randomized Trial of Web-Delivered Interventions for Blood Sugar Control for Individuals With Type 2 Diabetes

TypeinterventionalSponsorUniversity of MichiganRan2016 to 2017Enrolled44ConditionsDiabetes Mellitus, Type 2ArmsMulticomponent online program, Breath meter, Text messages, Diet-appropriate foods and cookbooks
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Laura R SaslowDepartment of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, United States.ORCID https://orcid.org/0000-0003-3991-3205
Judith Tedlie MoskowitzNorthwestern Medicine, Feinberg School of Medicine, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-1399-3318
Ashley E MasonOsher Center for Integrative Medicine, University of California San Francisco, San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-8744-0185
Jennifer DaubenmierDepartment of Health Education, San Francisco State University, San Francisco, CA, United States.ORCID https://orcid.org/0000-0001-5678-4068
Bradley LiestenfeltzDepartment of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, United States.ORCID https://orcid.org/0000-0001-9203-5881
Amanda L MisselDepartment of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, MI, United States.ORCID https://orcid.org/0000-0002-9879-0519
Hovig BayandorianORCID https://orcid.org/0000-0003-4596-0323
James E AikensDepartment of Family Medicine, University of Michigan, Ann Arbor, MI, United States.ORCID https://orcid.org/0000-0002-3795-9018
Sarah KimDivision of Endocrinology, Diabetes and Metabolism, University of California, San Francisco, San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-3599-5509
Frederick M HechtOsher Center for Integrative Medicine, University of California San Francisco, San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-5782-1171
University of Michigan · USUniversity of California, San Francisco · USNorthwestern Medicine · USSan Francisco State University · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Martin G Myers · 2013 to 2026
$24.3M
ZIDOVUDINE &LAMIVUDINE &NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFM01RR001271 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$22.7M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Mentoring and Research in Integrative MedicineK24AT007827 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M · 2013 to 2022
$1.8M
Pilot Projects CoreP20NR015331 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LARSON, JANET L. · 2014 to 2018
$1.3M
An experimental medicine approach toward the identification of a compulsive overeating phenotype in obesityK23HL133442 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MASON, ASHLEY E. · 2016 to 2020
$1.1M
Optimization of a Multicomponent Diet Intervention in Type 2 DiabetesK01DK107456 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SASLOW, LAURA · 2016 to 2020
$777k
Positive Affect Regulation for HIV Prevention in People with Mood DisordersK24MH093225 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MOSKOWITZ, JUDITH T. · 2011 to 2015
$713k
NCCIH NIH HHS K24 AT007827NCRR NIH HHS M01 RR001271NHLBI NIH HHS K23 HL133442NIDDK NIH HHS K01 DK107456NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK098722NIMH NIH HHS K24 MH093225NINR NIH HHS P20 NR015331
6 · The paper itself

Abstract

backgroundAdults with type 2 diabetes may experience health benefits, including glycemic control and weight loss, from following a very low-carbohydrate, ketogenic (VLC) diet. However, it is unclear which ancillary strategies may enhance these effects.

objectiveThis pilot study aims to estimate the effect sizes of 3 intervention enhancement strategies (text messages, gifts, and breath vs urine ketone self-monitoring) that may improve outcomes of a 12-month web-based ad libitum VLC diet and lifestyle intervention for adults with type 2 diabetes. The primary intervention also included other components to improve adherence and well-being, including positive affect and mindfulness as well as coaching.

methodsOverweight or obese adults (n=44; BMI 25-45 kg/m

resultsWe retained 73% (32/44) of the participants at 12 months. The intervention, across all conditions, led to improvements in glucose control and reductions in body weight at the 12-month follow-up. In intent-to-treat (ITT) analyses, the mean HbA

conclusionsText messages, gifts of food and cookbooks, and urine-based ketone self-monitoring may potentially enhance the glycemic or weight loss benefits of a web-based VLC diet and lifestyle intervention for individuals with type 2 diabetes. Future research could investigate other enhancement strategies to help create even more effective solutions for the treatment of type 2 diabetes.

trial registrationClinicalTrials.gov NCT02676648; http://clinicaltrials.gov/ct2/show/NCT02676648.

Indexed as

diet, ketogenicself-managementtext messagestype 2 diabetes

Identifiers

PMID32902391
PMCPMC7511867
OpenAlexW3083964361

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.