Evidence map›Paper›PMID 32901602›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Development of a Multiplex Bead Assay for the Detection of IgG Antibody Responses to Guinea Worm.

Jeffrey W Priest, Olga Stuchlik, Matthew Reed, Peter Soboslay, Vitaliano Cama, Sharon L Roy

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Guinea Worm Disease: A Neglected Diseases on the Verge of Eradication.Tropical medicine and infectious disease · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jeffrey W Priest1Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Olga Stuchlik2Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia.
Matthew Reed2Division of Scientific Resources, Centers for Disease Control and Prevention, Atlanta, Georgia.
Peter Soboslay3Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany.
Vitaliano Cama4Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Sharon L Roy4Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · USDivision of Parasitic Diseases and Malaria · USUniversity of Tübingen · DE

Funding

Wellcome Trust
6 · The paper itself

Abstract

The success of the Guinea Worm (GW) Eradication Program over the past three decades has been tempered by the persistence of GW disease in a few African nations and the potential for a future resurgence in cases. Domestic dogs are now a major concern as a disease reservoir as large numbers of cases of canine GW disease are now reported each year, mainly along the Chari River in Chad. As a first step toward the development of a serologic assay for dogs, archived human plasma samples from dracunculiasis-positive donors from Togo were used to select adult female GW antigens for peptide sequencing and cloning. Eight protein sequences of interest were expressed as recombinant glutathione-

Indexed as

AnimalsAntibodies, HelminthAntigens, HelminthBlotting, WesternCross ReactionsDisease EradicationDisease ReservoirsDog DiseasesDogsDracunculiasisDracunculus NematodeElectrophoresis, Polyacrylamide GelGlutathione TransferaseHumansImmunoglobulin GOnchocerca volvulusAntibodies, HelminthAntigens, HelminthGlutathione TransferaseImmunoglobulin GRecombinant Fusion ProteinsThioredoxins

Identifiers

PMID32901602
PMCPMC7695067
OpenAlexW4236229604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.