Evidence map›Paper›PMID 32901341›Full record

ArticleParasitology research2020

Immunomodulatory action of excretory-secretory products of Angiostrongylus cantonensis in a mouse tumour model.

Yajun Lu, Yuxiao Yang, Siqi Yang, Qianfeng Xia

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Bugs as drugs: parasite biomolecules as novel therapeutics against breast cancer.American journal of physiology. Cell physiology · 2026
    Review
  2. Article
  3. Parasites revive hope for cancer therapy.European journal of medical research · 2024
    Review
  4. Article
  5. The many faces of parasite calreticulin.Frontiers in immunology · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yajun LuKey Laboratory of Tropical Translational Medicine of Ministry of Education and School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, 571199, Hainan, China.ORCID https://orcid.org/0000-0002-8879-6570
Yuxiao YangKey Laboratory of Tropical Translational Medicine of Ministry of Education and School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, 571199, Hainan, China.
Siqi YangKey Laboratory of Tropical Translational Medicine of Ministry of Education and School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, 571199, Hainan, China.
Qianfeng XiaKey Laboratory of Tropical Translational Medicine of Ministry of Education and School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, 571199, Hainan, China. xiaqianfeng@hainmc.edu.cn.ORCID http://orcid.org/0000-0002-5737-4842
Hainan Medical University · CN

Funding

Education Department of Hainan Province Hnky2017ZD-15Hainan Medical University HY2015-08
6 · The paper itself

Abstract

Excretory-secretory products (ESPs) of parasitic helminths are well known to exert immunostimulation and immunomodulation in hosts. Immune regulation plays a key role in anti-tumour therapy. The present study explored the anti-tumour effect of ESPs released by Angiostrongylus cantonensis. In Hepa1-6 mouse tumour models, ESPs significantly reduced tumour growth. Tumour-bearing mice treated with ESPs had significantly higher CD3

Indexed as

A549 CellsAngiostrongylus cantonensisAnimalsApoptosisCalreticulinDisease Models, AnimalEndoplasmic Reticulum StressEscherichia coliHelminth ProteinsHep G2 CellsHumansImmunologic FactorsMiceNeoplasmsRecombinant ProteinsCalreticulinHelminth ProteinsImmunologic FactorsRecombinant ProteinsAngiostrongylus cantonensisApoptosisCalreticulinEndoplasmic reticulum stressExcretory-secretory productsTumour

Identifiers

PMID32901341
OpenAlexW3085432701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.