ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Dental status and risk of odontogenic complication in patients undergoing hematopoietic stem cell transplant.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Systemic implications of endodontic and periodontal infections in hematopoietic stem cell transplantation: a systematic review.Clinical oral investigations · 2025Pooled it
- Association between oral ulcerative lesions, oral infections, and fever during the pre-engraftment phase after hematopoietic cell transplantation: results from the Orastem study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Oral disease burden in children and adolescents scheduled for allogeneic haematopoietic stem cell transplantation: a multicentre study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Impact of health insurance coverage on dentition status prior to hematopoietic cell transplant: A 10-year single-institution observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Article
- Beyond Oral Health: Personalized Strategies for Managing Oral Infections in Neutropenic Patients.Journal of personalized medicine · 2026Review
- A retrospective cohort study of the oral healthcare needs of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Oral Hygiene Management of Hematologic Patients Undergoing Auto-Transplantation: An Observational Study.Dentistry journal · 2025Article
- A sex-dependent salivary bacterium influences oral mucositis severity after allogeneic hematopoietic cell transplantation.NPJ biofilms and microbiomes · 2024Article
- Oral foci of infection and their relationship with hospital stay after haematopoietic cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Do oral conditions influence the incidence of bloodstream infection after hematopoietic stem cell transplantation? A retrospective study in Japan.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- The prevalence of apical periodontitis in patients prior to hematopoietic cell transplantation: a systematic review.Restorative dentistry & endodontics · 2024Review
- Dental evaluation and clearance prior to allogeneic hematopoietic cell transplantation.Oral diseases · 2024Article
- Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study.PloS one · 2023Observational
- Structural Changes in Resin-Based Composites in Saliva of Patients with Leukemia before Starting Chemotherapeutic Regimen.Polymers · 2022Article
- Brazilian dental consensus on dental management in hematopoietic stem cell transplantation - Part I - pre-HSCT.Hematology, transfusion and cell therapyReview
- Assessment of oral health condition in recipients of allogeneic hematopoietic cell transplantation.Hematology, transfusion and cell therapyArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeDental evaluation and management prior to hematopoietic stem cell transplant (HSCT) plays a vital role in identifying and treating infections that may be life-threatening. The purpose of this study is to describe the dental management of patients undergoing pre-HSCT examination with the Dental Service at Memorial Sloan Kettering Cancer Center (MSKCC) and to report on odontogenic complications.
methodsPatients referred for evaluation as part of the standard preparation for HSCT were included. Following clinical and radiological examination, patients were assigned to one of three groups based on risk of odontogenic infection, and treatment was provided as indicated. Patients were followed, and their medical records were reviewed for odontogenic complications during the transplant admission.
resultsOf the 375 patients evaluated, 350 patients underwent HSCT: allogeneic 143 (40.9%) and autologous 207 (59.1%). The distribution of primary cancer diagnosis was as follows: multiple myeloma 104 (29.7%), leukemias 95 (27.1%), Hodgkin's lymphoma 28 (8.0%), non-Hodgkin's Lymphoma 99 (28.3%), and other conditions 24 (6.9%). The median time from dental evaluation to transplant was 29 days. The median Decayed, Missing, Filled Teeth Index was 17. The median Community Periodontal Index was 1. Based on dental status, 145 patients (41.4%) were classified as low risk, 133 (38%) as moderate risk and 72 (20.6%) as high risk of odontogenic infection. One hundred fourteen patients (32.6%) required dental treatment prior to HSCT, and 100 of these (28.6%) completed treatment. Two (0.57%) patients had odontogenic complications.
conclusionsWith conservative pre-HSCT dental treatment based on an infection risk classification system, a low odontogenic complication rate was observed.
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