Evidence map›Paper›PMID 32901068›Full record

ArticleScientific reports2020

Ethnic variation of oral microbiota in children.

Thyagaseely S Premaraj, Raven Vella, Jennifer Chung, Qingqi Lin, Panier Hunter, Kori Underwood, Sundaralingam Premaraj, Yanjiao Zhou

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Article
  8. The role ofFrontiers in oral health · 2026
    Review
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  10. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Thyagaseely S PremarajCollege of Dentistry, University of Nebraska Medical Center, Lincoln, NE, USA.
Raven VellaDepartment of Medicine, UCONN Health Center, 263 Farmington Ave, Farmington, CT, 06030, USA.
Jennifer ChungDepartment of Medicine, UCONN Health Center, 263 Farmington Ave, Farmington, CT, 06030, USA.
Qingqi LinDepartment of Medicine, UCONN Health Center, 263 Farmington Ave, Farmington, CT, 06030, USA.
Panier HunterDepartment of Medicine, UCONN Health Center, 263 Farmington Ave, Farmington, CT, 06030, USA.
Kori UnderwoodCollege of Dentistry, University of Nebraska Medical Center, Lincoln, NE, USA.
Sundaralingam PremarajCollege of Dentistry, University of Nebraska Medical Center, Lincoln, NE, USA.
Yanjiao ZhouDepartment of Medicine, UCONN Health Center, 263 Farmington Ave, Farmington, CT, 06030, USA. yazhou@uchc.edu.
UConn Health · USUniversity of Nebraska Medical Center · USJackson Laboratory · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
UNMC Histology/Imaging and Creighton University Imaging Core FacilityP30GM110768 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WALSH, EDWARD J · 2014 to 2018
$5.1M
NCI NIH HHS P30 CA036727NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P30 GM110768
6 · The paper itself

Abstract

Despite widely used preventive measures such as sealant programs to control caries prevalence, disparities are seen among ethnic groups. Supragingival plaque harbors hundreds of bacterial species, playing a significant role in oral health and disease. It is unknown whether the ethnic variation influences the supragingival microbiota in children. In our study, variations in microbiota of the supragingival plaque was investigated from 96 children between 6 and 11 years old in four ethnic groups (African American, Burmese, Caucasian, and Hispanic) from the same geographic location by 16S rRNA gene sequencing. We found that the microbial alpha and beta diversity of supragingival microbiota significantly differed between ethnic groups. The supragingival plaque microbiota had the most complex microbial community in Burmese children. Within-group microbiota similarity in Burmese or Caucasian children was significantly higher than between-groups similarity. We identified seven ethnic group-specific bacterial taxa after adjusting for dental plaque index, decayed missing filled teeth (DMFT) and the frequency of brushing. Children with high plaque index and high DMFT values were more similar to each other in the overall microbial community, compared to low plaque index or low DMFT groups in which inter-subject variation is high. Several bacterial taxa associated with high plaque index or high DMFT were ethnic group-specific. These results demonstrated that supragingival microbiota differed among ethnicity groups in children.

Indexed as

BacteriaChildDental CariesDental PlaqueEthnicityFemaleHumansMaleMicrobiotaOral HealthRNA, Ribosomal, 16SSalivaUnited StatesRNA, Ribosomal, 16S

Identifiers

PMID32901068
PMCPMC7478955
OpenAlexW3084108988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.