Evidence map›Paper›PMID 32900960›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

The primary step of biotin synthesis in mycobacteria.

Zhe Hu, John E Cronan

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhe HuDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0002-6864-2099
John E CronanDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801; j-cronan@illinois.edu.ORCID 0000-0002-7064-312X

Funding

GENETIC APPROACHES TO REGULATION OF LIPID METABOLISMR01AI015650 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI CRONAN, JOHN E. · 1985 to 2022
$12.0M
GENETIC APPROACHES TO REGULATION OF LIPID METABOLISMR37AI015650 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI CRONAN, JOHN E. · 1994 to 2003
$1.8M
NIAID NIH HHS R01 AI015650NIAID NIH HHS R37 AI015650
6 · The paper itself

Abstract

Biotin plays an essential role in growth of mycobacteria. Synthesis of the cofactor is essential for

Indexed as

Mycobacterium smegmatisMycobacterium tuberculosisBacterial ProteinsBiotinEscherichia coliMetabolic Networks and PathwaysProtein O-MethyltransferaseBacterial ProteinsBiotinProtein O-MethyltransferasebiotinligationmycobacteriaO-methyltransferase

Identifiers

PMID32900960
PMCPMC7519262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.