ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
Multiple Midfrontal Thetas Revealed by Source Separation of Simultaneous MEG and EEG.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Trial
- Frustrative nonreward engages midfrontal theta power and modulates effort expenditure.Cognitive, affective & behavioral neuroscience · 2026Article
- Midfrontal theta power relates to response speeding following frustrative nonreward.NeuroImage · 2026Article
- FREQ-NESS Reveals Age-Related Differences in Frequency-Resolved Brain Networks During Auditory Recognition and Resting State.Annals of the New York Academy of Sciences · 2026Article
- Dissociating Contributions of Theta and Alpha Oscillations from Aperiodic Neural Activity in Human Visual Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Revisiting alpha-theta cross-frequency dynamics during working memory.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Reduced task-induced frontal midline theta activity in chronic stroke patients compared to healthy older adults - An MEG study.NeuroImage. Clinical · 2026Article
- BROAD-NESS Uncovers Dual-Stream Mechanisms Underlying Predictive Coding in Auditory Memory Networks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Attention- and action-related oscillatory dynamics in a visuomotor network.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- FREQ-NESS Reveals the Dynamic Reconfiguration of Frequency-Resolved Brain Networks During Auditory Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Beyond uniformity: individual sensitivities to reward and punishment shape midfrontal-theta responses to approach avoidance conflict.Social cognitive and affective neuroscience · 2025Article
- Basal ganglia components have distinct computational roles in decision-making dynamics under conflict and uncertainty.PLoS biology · 2025Article
- Neural signatures of prioritization and facilitation in retrieving repeated items in visual working memory.Frontiers in human neuroscience · 2025Article
- EEG alpha and theta time-frequency structure during a written mathematical task.Medical & biological engineering & computing · 2024Article
- Midfrontal mechanisms of performance monitoring continuously adapt to incoming information during outcome anticipation.Neuroimage. Reports · 2023Article
- Posterior theta activity reveals an early signal of self-face recognition.Scientific reports · 2023Article
- Modeling brain dynamics and gaze behavior: Starting point bias and drift rate relate to frontal midline theta oscillations.NeuroImage · 2023Article
- Novelty-induced frontal-STN networks in Parkinson's disease.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Midfrontal theta is associated with errors, but no evidence for a link with error-related memory.Neuroimage. Reports · 2022Article
- Midfrontal Theta Activity Is Sensitive to Approach-Avoidance Conflict.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Theta-band (∼6 Hz) rhythmic activity within and over the medial PFC ("midfrontal theta") has been identified as a distinctive signature of "response conflict," the competition between multiple actions when only one action is goal-relevant. Midfrontal theta is traditionally conceptualized and analyzed under the assumption that it is a unitary signature of conflict that can be uniquely identified at one electrode (typically FCz). Here we recorded simultaneous MEG and EEG (total of 328 sensors) in 9 human subjects (7 female) and applied a feature-guided multivariate source-separation decomposition to determine whether conflict-related midfrontal theta is a unitary or multidimensional feature of the data. For each subject, a generalized eigendecomposition yielded spatial filters (components) that maximized the ratio between theta and broadband activity. Components were retained based on significance thresholding and midfrontal EEG topography. All of the subjects individually exhibited multiple (mean 5.89, SD 2.47) midfrontal components that contributed to sensor-level midfrontal theta power during the task. Component signals were temporally uncorrelated and asynchronous, suggesting that each midfrontal theta component was unique. Our findings call into question the dominant notion that midfrontal theta represents a unitary process. Instead, we suggest that midfrontal theta spans a multidimensional space, indicating multiple origins, but can manifest as a single feature at the sensor level because of signal mixing.
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