Evidence map›Paper›PMID 32900827›Full record

ArticleJournal of bacteriology2020

Nanoluciferase Reporter Mycobacteriophage for Sensitive and Rapid Detection of Mycobacterium tuberculosis Drug Susceptibility.

Paras Jain, Spencer Garing, Deepshikha Verma, Rajagopalan Saranathan, Nicholas Clute-Reinig, Jacob Gadwa, Chelsea Peterson, Gleda Hermansky, Anna Astashkina Fernandez, Emmanuel Asare and 11 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The unique role ofmBio · 2026
    Article
  6. Review
  7. Article
  8. Luciferase reporter mycobacteriophage (TM4::Journal of clinical microbiology · 2025
    Article
  9. Mycobacteriophage-mediated gene transfer enables in vitro drug screening and in vivo tracking ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Rapid detection of drug resistance inFrontiers in cellular and infection microbiology · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Paras JainIntellectual Ventures Laboratory, Bellevue, Washington, USA parasjain29@gmail.com kyle.minch@ghlabs.org.
Spencer GaringIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Deepshikha VermaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Rajagopalan SaranathanDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Nicholas Clute-ReinigIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Jacob GadwaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Chelsea PetersonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Gleda HermanskyIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Anna Astashkina FernandezIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Emmanuel AsareDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Torin R WeisbrodDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Ethan SpencerIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Claire V MulhollandDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Michael BerneyDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
David BellIntellectual Ventures' Global Good Fund, Bellevue, Washington, USA.
Kevin P NicholsIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Anne-Laure M Le NyIntellectual Ventures Laboratory, Bellevue, Washington, USA.
Diane OrdwayMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0003-3321-3080
Akos SomoskoviIntellectual Ventures' Global Good Fund, Bellevue, Washington, USA.
Kyle J MinchIntellectual Ventures Laboratory, Bellevue, Washington, USA parasjain29@gmail.com kyle.minch@ghlabs.org.ORCID 0000-0003-2447-5759
Bellevue Hospital Center · USAlbert Einstein College of Medicine · USColorado State University · USIntellectual Ventures (United States) · USTrudeau Institute · US

Funding

Molecular Genetic Analysis of Mycobacterium TuberculosisR37AI026170 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI WILLIAM Robert JACOBS · 2004 to 2026
$7.7M
NIAID NIH HHS R37 AI026170
6 · The paper itself

Abstract

Phenotypic testing for drug susceptibility of

Indexed as

Drug Resistance, BacterialAntitubercular AgentsHumansLuciferasesLuminescent MeasurementsMicrobial Sensitivity TestsMycobacteriophagesMycobacterium tuberculosisRifampinTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryAntitubercular AgentsLuciferasesRifampinbacteriophagesdrug screeningdrug susceptibility testingMycobacterium tuberculosisnanoluciferasephage

Identifiers

PMID32900827
PMCPMC7585058
OpenAlexW3083076737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.