Evidence map›Paper›PMID 32900701›Full record

ArticleBMJ open diabetes research & care2020

β-Cell function or insulin resistance was associated with the risk of type 2 diabetes among women with or without obesity and a history of gestational diabetes.

Yuxin Fan, Leishen Wang, Huikun Liu, Shuang Zhang, Huiguang Tian, Yun Shen, Jaakko Tuomilehto, Zhijie Yu, Xilin Yang, Gang Hu and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Associations Between Diabetes Mellitus and Neurodegenerative Diseases.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Associations between Diabetes Mellitus and Selected Cancers.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Yuxin FanDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Leishen WangTianjin Women's and Children's Health Center, Tianjin, China.
Huikun LiuTianjin Women's and Children's Health Center, Tianjin, China.
Shuang ZhangTianjin Women's and Children's Health Center, Tianjin, China.
Huiguang TianTianjin Women's and Children's Health Center, Tianjin, China.
Yun ShenChronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Jaakko TuomilehtoDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Zhijie YuPopulation Cancer Research Program, Dalhousie University, Halifax, Nova Scotia, Canada.
Xilin YangDepartment of Epidemiology, School of Public Health, Tianjin Medical University, Tianjin, China.
Gang HuChronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA gang.hu@pbrc.edu mingliu@tmu.edu.cn.ORCID 0000-0002-6172-8017
Ming LiuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China gang.hu@pbrc.edu mingliu@tmu.edu.cn.ORCID 0000-0003-2665-4072
Tianjin Children's Hospital · CNPennington Biomedical Research Center · USDalhousie University · CATianjin Medical University · CNTianjin Medical University General Hospital · CNUniversity of Helsinki · FI

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Methylomics of prenatal GDM: Natural history & lifestyle intervention in childrenR01DK100790 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BACCARELLI, ANDREA, HOU, LIFANG · 2014 to 2017
$2.6M
NIDDK NIH HHS R01 DK100790NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

introductionTo evaluate the single association of postpartum β-cell dysfunction and insulin resistance (IR), as well as different combinations of postpartum β-cell dysfunction, IR, obesity, and a history of gestational diabetes mellitus (GDM) with postpartum type 2 diabetes risk. RESEARCH DESIGN AND

methodsThe study included 1263 women with prior GDM and 705 women without GDM. Homeostatic model assessment was used to estimate homeostatic model assessment of β-cell secretory function (HOMA-%β) and homeostatic model assessment of insulin resistance (HOMA-IR).

resultsMultivariable-adjusted ORs of diabetes across quartiles of HOMA-%β and HOMA-IR were 1.00, 1.46, 2.15, and 6.25 (p

conclusionsβ-cell dysfunction or IR was significantly associated with postpartum diabetes. IR and β-cell dysfunction, together with obesity and a history of GDM, had the highest ORs of postpartum diabetes risk.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2Insulin ResistanceInsulin-Secreting CellsFemaleHumansObesityPregnancyinsulin resistancenon-insulin-treated type 2 diabetesobesity

Identifiers

PMID32900701
PMCPMC7478009
OpenAlexW3084184939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.