SynthesisClinical journal of the American Society of Nephrology : CJASN2021
Pathophysiology and Treatment of Enteric Hyperoxaluria.
Synthesis in Clinical journal of the American Society of Nephrology : CJASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Vascular calcification on the risk of kidney stone: a meta-analysis.Renal failure · 2023Pooled it
- Controlled colonization of the human gut with a genetically engineered microbial therapeutic.Science (New York, N.Y.) · 2025Trial
- Determinants of enteric hyperoxaluria in the SAMP1/YitFc mouse model of spontaneous ileitis.Gut microbes · 2026Article
- Gut microbiota: a novel key player in urinary stone formation - from oxalate metabolism to systemic regulation.Gut microbes · 2026Review
- Animal Models of Hyperoxaluria and Their Relevance for Fundamental Research and Clinical Practice.International journal of molecular sciences · 2026Review
- The Kidneys Went Nuts: Oxalate Nephropathy From Excessive Cashew Nut Consumption.Kidney medicine · 2026Article
- Nephrocalcinosis Following Roux-en-Y Gastric Bypass Secondary to Suspected Enteric Hyperoxaluria: A Case Report.Cureus · 2026Article
- Article
- Severe Acute Kidney Injury Following Whipple Procedure.Kidney360 · 2026Article
- An Unusual Cause of Oxalate Nephropathy: Acute Kidney Injury After Ingestion of Dried Bilimbi Fruit.Cureus · 2026Article
- Predicting probiotic success: lessons from Oxalobacter and oxalate metabolism.NPJ biofilms and microbiomes · 2026Review
- Prevalence and risk factors for nephrolithiasis in adults with cystic fibrosis: A retrospective cohort study.PloS one · 2026Article
- Gastrointestinal resection is associated with urolithiasis severity among inflammatory bowel disease patients.The Canadian journal of urology · 2025Article
- Improved 24-hour urine parameters associated with reduced symptomatic kidney stone recurrence.Urolithiasis · 2025Article
- Oxalate nephropathy causing renal failure in small bowel Crohn's disease: a case report.Journal of medical case reports · 2025Article
- Gut to Stone: The Woes of Malabsorption and Kidney Stone Growth.Kidney international reports · 2025Article
- Hyperoxaluria: Diagnosis and Treatment.The Urologic clinics of North America · 2025Review
- Spontaneous ileitis and postsurgical murine models of enteric hyperoxaluria.American journal of physiology. Gastrointestinal and liver physiology · 2025Article
- Role of pancreatic lipase inhibition in obesity treatment: mechanisms and challenges towards current insights and future directions.International journal of obesity (2005) · 2025Review
- Oxalate nephropathy precipitated by linaclotide in a high-risk patient.Clinical nephrology. Case studies · 2025Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 2 countries.
Funding
Abstract
Enteric hyperoxaluria is a distinct entity that can occur as a result of a diverse set of gastrointestinal disorders that promote fat malabsorption. This, in turn, leads to excess absorption of dietary oxalate and increased urinary oxalate excretion. Hyperoxaluria increases the risk of kidney stones and, in more severe cases, CKD and even kidney failure. The prevalence of enteric hyperoxaluria has increased over recent decades, largely because of the increased use of malabsorptive bariatric surgical procedures for medically complicated obesity. This systematic review of enteric hyperoxaluria was completed as part of a Kidney Health Initiative-sponsored project to describe enteric hyperoxaluria pathophysiology, causes, outcomes, and therapies. Current therapeutic options are limited to correcting the underlying gastrointestinal disorder, intensive dietary modifications, and use of calcium salts to bind oxalate in the gut. Evidence for the effect of these treatments on clinically significant outcomes, including kidney stone events or CKD, is currently lacking. Thus, further research is needed to better define the precise factors that influence risk of adverse outcomes, the long-term efficacy of available treatment strategies, and to develop new therapeutic approaches.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.