Evidence map›Paper›PMID 32900331›Full record

ArticleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2020

A pilot study of high frequency accelerometry-based sedation and agitation monitoring in critically ill patients.

Mark Weeden, Nandakishor Desai, Shyamala Sriram, Marimuthu Swami Palaniswami, Bo Wang, Lachlan Talbot, Adam Deane, Rinaldo Bellomo, Bernard Yan

Abstract read
In one paragraph

Article in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Comparison of Quantium Consciousness Index and Richmond Agitation Sedation Scale in Mechanically Ventilated Critically Ill Patients: An Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mark WeedenDepartment of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia. weeden.mark.c@gmail.com.
Nandakishor DesaiDepartment of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, VIC, Australia.
Shyamala SriramDepartment of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Marimuthu Swami PalaniswamiDepartment of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, VIC, Australia.
Bo WangMelbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia.
Lachlan TalbotDepartment of Neuroscience, University of Melbourne, Melbourne, VIC, Australia.
Adam DeaneDepartment of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Rinaldo BellomoDepartment of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Bernard YanMelbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe degree of sedation or agitation in critically ill patients is typically assessed with the Richmond Agitation and Sedation Scale (RASS). However, this approach is intermittent and subject to unrecognised variation between assessments. High frequency accelerometry may assist in achieving a quantitative and continuous assessment of sedation while heralding imminent agitation.

designWe undertook a prospective, observational pilot study.

settingAn adult tertiary intensive care unit in Melbourne, Australia.

participants20 patients with an admission diagnosis of trauma.

main outcome measuresAccelerometers were applied to patients' wrists and used to continuously record patient movement. Video data of patient behaviour were simultaneously collected, and observers blinded to accelerometry data were adjudicated the RASS score every 30 seconds. Exploratory analyses were undertaken.

resultsPatients were enrolled for a median duration of 9.7 hours (interquartile range [IQR], 0-22.8) and a total of 160 hours. These patients had a median RASS score of 0 (IQR, -4 to 0). A 2-minute moving window of amplitude variance was seen to reflect contemporaneous fluctuations in motor activity and was proportional to the RASS score. Furthermore, the moving window of amplitude variance was observed to spike immediately before ≥ 2 point increases in the RASS score.

conclusionsWe describe a novel approach to the analysis of wrist accelerometry data in critically ill patients. This technique not only appears to provide novel and continuous information about the depth of sedation or degree of agitation, it is also notable in its aptitude to anticipate impending transitions to higher RASS values.

Indexed as

ConsciousnessCritical IllnessPsychomotor AgitationAccelerometryAdultAustraliaCritical CareHumansPilot ProjectsProspective Studies

Identifiers

PMID32900331
PMCPMC10699079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.