ArticleMicroorganisms2020
Development and Validation of an In-House Library for Filamentous Fungi Identification by MALDI-TOF MS in a Clinical Laboratory in Medellin (Colombia).
Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Validation of the Mycelium Transfer Method Coupled with MALDI-TOF MS for Rapid Identification of Filamentous Fungi.Pathogens (Basel, Switzerland) · 2026Article
- Rapid identification of Sporothrix brasiliensis by MALDI-TOF MS directly from clinical cultures in an Amazonian epidemic setting.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Rapid MALDI-TOF Mass Spectrometry Identification of the Chalkbrood PathogenJournal of fungi (Basel, Switzerland) · 2026Article
- Identification of Challenging Dermatophyte Species Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.Journal of fungi (Basel, Switzerland) · 2025Article
- Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: A breakthrough in rapid and precise mold identification.Current medical mycology · 2025Article
- Formic acid sandwich method is well-suited for filamentous fungi identification and improves turn around time using Zybio EXS2600 mass spectrometry.BMC microbiology · 2024Article
- Filamentous Fungal Keratitis in Greece: A 16-Year Nationwide Multicenter Survey.Mycopathologia · 2022Article
- Mass spectrometry in research laboratories and clinical diagnostic: a new era in medical mycology.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Review
- Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) Analysis for the Identification of Pathogenic Microorganisms: A Review.Microorganisms · 2021Review
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Identification of filamentous fungi by conventional phenotypic methods are time-consuming, and a correct identification at the species level is prone to errors. Therefore, a more accurate and faster time-to-results, and cost-effective technique, is required, such as the Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS). In this study, we describe the development of an in-house spectra library for the identification of filamentous fungi frequently isolated from patients with infections. An in-house spectra library was constructed using 14 reference strains grown in solid medium. Clinical isolates were identified either by the in-house spectra library or the Biotyper commercial library from Bruker Daltonics. Fungal identification was carried following the Biotyper's established scores: ≤1.699: not reliably identified (NRI); 1.700-1.999: genus-level; ≥2.000: species-level. Clinical isolates were identified, with the in-house library, at species- and genus-level at 88.70% (55) and 3.22% (2), respectively. While 4.80% (3) was NRI and 3.22% (2) was discrepant concerning sequencing. On the contrary, identification up to species and genus-level with the commercial library was 44.44% (16) and 22.22% (8), respectively. NRI and the discrepancy was 30.55% (11) and 2.77% (1), respectively. For the reaming 26 isolates, 16 from
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