Evidence map›Paper›PMID 32899962›Full record

ArticleMetabolites2020

Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in

Chloé Simard, Andréa Lebel, Eric Pierre Allain, Mohamed Touaibia, Etienne Hebert-Chatelain, Nicolas Pichaud

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chloé SimardDepartment of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada.
Andréa LebelDepartment of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada.
Eric Pierre AllainAtlantic Cancer Research Institute (ACRI), Moncton, NB E1C 8X3, Canada.
Mohamed TouaibiaDepartment of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada.ORCID 0000-0003-3744-8012
Etienne Hebert-ChatelainDepartment of Biology, Université de Moncton, Moncton, NB E1A 3E9, Canada.ORCID 0000-0003-1480-2787
Nicolas PichaudDepartment of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada.ORCID 0000-0002-2820-8124
Université de Moncton · CAAtlantic Cancer Research Institute · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2017-05100New Brunswick Innovation Foundation NAUniversité de Moncton NA
6 · The paper itself

Abstract

In insect, pyruvate is generally the predominant oxidative substrate for mitochondria. This metabolite is transported inside mitochondria via the mitochondrial pyruvate carrier (MPC), but whether and how this transporter controls mitochondrial oxidative capacities in insects is still relatively unknown. Here, we characterize the importance of pyruvate transport as a metabolic control point for mitochondrial substrate oxidation in two genotypes of an insect model,

Indexed as

drosophilakineticsmetabolomicsmitochondrial pyruvate carriermitochondrial respiration

Identifiers

PMID32899962
PMCPMC7570025
OpenAlexW3083111306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.