Evidence map›Paper›PMID 32899792›Full record

ArticleInternational journal of molecular sciences2020

Novel ANO1 Inhibitor from

Yohan Seo, Nguyen Hoang Anh, Yunkyung Heo, So-Hyeon Park, Phan Van Kiem, Yechan Lee, Duong Thi Hai Yen, Sungwoo Jo, Dongkyu Jeon, Bui Huu Tai and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Inhibition of ANO1 byInternational journal of molecular sciences · 2023
    Article
  7. Role of ANO1 in tumors and tumor immunity.Journal of cancer research and clinical oncology · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Yohan SeoCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Nguyen Hoang AnhGraduate University of Sciences and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Yunkyung HeoCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
So-Hyeon ParkCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.ORCID 0000-0003-0414-6245
Phan Van KiemGraduate University of Sciences and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Yechan LeeCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Duong Thi Hai YenInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Sungwoo JoCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Dongkyu JeonCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Bui Huu TaiGraduate University of Sciences and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Nguyen Hoai NamInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Chau Van MinhInstitute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Seung Hyun KimCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.ORCID 0000-0003-2613-0674
Nguyen Xuan NhiemGraduate University of Sciences and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Wan NamkungCollege of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Yonsei University · KRVietnam Academy of Science and Technology · VN

Funding

National Research Foundation of Korea NRF-2015R1D1A1A01057695National Research Foundation of Korea NRF-2018R1A6A1A03023718National Research Foundation of Korea NRF-2019R1I1A1A01061117Vietnam Academy of Science and Technology DL0000.01/19-20
6 · The paper itself

Abstract

Anoctamin1 (ANO1), a calcium-activated chloride channel, is frequently overexpressed in several cancers, including human prostate cancer and oral squamous cell carcinomas. ANO1 plays a critical role in tumor growth and maintenance of these cancers. In this study, we have isolated two new compounds (

Indexed as

AnimalsAnoctamin-1Antineoplastic AgentsApoptosisCalciumCalcium SignalingCarcinoma, Squamous CellCell Line, TumorCell ProliferationCell SurvivalChloride ChannelsHumansMallotus PlantMouth NeoplasmsNeoplasm ProteinsPC-3 CellsANO1 protein, humanANO1 protein, ratAnoctamin-1Antineoplastic AgentsCalciumChloride ChannelsNeoplasm ProteinsPlant Extractsanoctamin 1apoptosiscytotoxicityinhibitorMallotus apelta

Identifiers

PMID32899792
PMCPMC7576493
OpenAlexW3083322685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.