Evidence map›Paper›PMID 32899784›Full record

ArticleInternational journal of molecular sciences2020

A Mechanosensitive Channel, Mouse Transmembrane Channel-Like Protein 1 (Mtmc1) Is Translated from a Splice Variant

Soichiro Yamaguchi, Maho Hamamura, Ken-Ichi Otsuguro

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Soichiro YamaguchiLaboratory of Physiology, Department of Basic Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Maho HamamuraLaboratory of Pharmacology, Department of Basic Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Ken-Ichi OtsuguroLaboratory of Pharmacology, Department of Basic Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.ORCID 0000-0002-2481-5592
Hokkaido University · JP

Funding

Japan Society for the Promotion of Science 16K08066Takeda Science Foundation NATHE AKIYAMA LIFE SCIENCE FOUNDATION NAUehara Memorial Foundation NA
6 · The paper itself

Abstract

Mechanical stimuli caused by sound waves are detected by hair cells in the cochlea through the opening of mechanoelectrical transduction (MET) channels. Transmembrane channel-like protein 1 (TMC1) has been revealed to be the pore-forming component of the MET channel. The two splice variants for mouse

Indexed as

Alternative SplicingAnimalsCochleaHair Cells, AuditoryMaleMechanoreceptorsMechanotransduction, CellularMembrane ProteinsMiceMice, Inbred C57BLMutagenesis, Site-DirectedMutationProtein IsoformsMembrane ProteinsProtein IsoformsTMC1 protein, mouseKozak sequencemechanosensitive channelTmc1translationupstream open reading frame

Identifiers

PMID32899784
PMCPMC7554986
OpenAlexW3083543387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.