Evidence map›Paper›PMID 32899630›Full record

ArticleInternational journal of molecular sciences2020

Neuroprotection by Neurotropin through Crosstalk of Neurotrophic and Innate Immune Receptors in PC12 Cells.

Yu Fukuda, Kazuki Nakajima, Tatsuro Mutoh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Editorial for Special Issue "Gangliosides: Modes of Action and Cell Fates".International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Yu FukudaDepartment of Neurology and Neuroscience, Fujita Health University Hospital, Toyoake, Aichi 470-1192, Japan.ORCID 0000-0001-5737-2401
Kazuki NakajimaCenter for joint research facilities support, Research Promotion and Support Headquarters, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan.
Tatsuro MutohDepartment of Neurology and Neuroscience, Fujita Health University Hospital, Toyoake, Aichi 470-1192, Japan.ORCID 0000-0001-7712-8481
Fujita Health University · JPFujita Health University Hospital · JPNippon Zoki (Japan) · JP

Funding

Japan Society for the Promotion of Science London JP 16k09685
6 · The paper itself

Abstract

Infected or damaged tissues release multiple "alert" molecules such as alarmins and damage-associated molecular patterns (DAMPs) that are recognized by innate immune receptors, and induce tissue inflammation, regeneration, and repair. Recently, an extract from inflamed rabbit skin inoculated with vaccinia virus (Neurotropin

Indexed as

AnimalsGangliosidesImmunity, InnateMembrane MicrodomainsMembrane ProteinsNerve Growth FactorNeuritesNeuroprotectionNeuroprotective AgentsPC12 CellsPhosphorylationPolysaccharidesProto-Oncogene Proteins c-fynRatsReceptor Cross-TalkReceptor, trkAflotillinsGangliosidesMembrane ProteinsNerve Growth FactorNeuroprotective AgentsneurotropinPolysaccharidesProto-Oncogene Proteins c-fynReceptor, trkAFynGM1 ganglioside (GM1)lipid raftsNeurotropinToll-like receptor4 (TLR4)TrkA tyrosine kinase

Identifiers

PMID32899630
PMCPMC7555716
OpenAlexW3083573863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.