Evidence map›Paper›PMID 32899608›Full record

ArticleInternational journal of molecular sciences2020

Elucidating the Role of Ezh2 in Tolerogenic Function of NOD Bone Marrow-Derived Dendritic Cells Expressing Constitutively Active Stat5b.

Echarki Zerif, Farhan Ullah Khan, Ahmed Aziz Raki, Véronique Lullier, Denis Gris, Gilles Dupuis, Abdelaziz Amrani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Echarki ZerifDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.
Farhan Ullah KhanDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.
Ahmed Aziz RakiDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.
Véronique LullierDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.
Denis GrisDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.ORCID 0000-0003-1215-2434
Gilles DupuisDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.ORCID 0000-0003-4216-5201
Abdelaziz AmraniDepartment of Pediatric, Immunology division, Centre de Recherche Clinique du CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001-12th Avenue North, Sherbrooke, QC J1H 5N4, Canada.
Université de Sherbrooke · CA

Funding

CIHR MOP-300762Natural Sciences and Engineering Research Council of Canada RGPIN-2015-03671
6 · The paper itself

Abstract

Tolerogenic dendritic cells (toDCs) are crucial to controlling the development of autoreactive T cell responses and the prevention of autoimmunity. We have reported that NOD.CD11c

Indexed as

Adoptive TransferAnimalsAutoimmunityBone MarrowCD11c AntigenCell DifferentiationDendritic CellsDiabetes Mellitus, Type 1Enhancer of Zeste Homolog 2 ProteinGranulocyte-Macrophage Colony-Stimulating FactorHumansImmune ToleranceInterferon Regulatory Factor-4Interferon Regulatory Factor-8Interferon Regulatory FactorsMaleCD11c AntigenEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanGranulocyte-Macrophage Colony-Stimulating FactorInterferon Regulatory Factor-4Interferon Regulatory Factor-8Interferon Regulatory FactorsStat5b protein, mouseSTAT5 Transcription Factorhistone methyltransferaseInterferon Regulatory Factor 4 and 8nonobese diabetic miceStat5b transcription factortolerogenic dendritic cellstype 1 diabetes

Identifiers

PMID32899608
PMCPMC7554732
OpenAlexW2995043367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.