Evidence map›Paper›PMID 32899499›Full record

ArticleJournal of clinical medicine2020

Safety and Tolerability of Plasma Exchange and Immunoadsorption in Neuroinflammatory Diseases.

Johannes Dorst, Frank Fillies, Jens Dreyhaupt, Makbule Senel, Hayrettin Tumani

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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  16. Apheresis in Neurological Disorders.Journal of clinical medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Johannes DorstDepartment of Neurology, University of Ulm, 89081 Ulm, Germany.ORCID 0000-0001-6352-0909
Frank FilliesDepartment of Neurology, University of Ulm, 89081 Ulm, Germany.
Jens DreyhauptInstitute for Epidemiology and Medical Biometry, University of Ulm, 89081 Ulm, Germany.ORCID 0000-0001-8057-161X
Makbule SenelDepartment of Neurology, University of Ulm, 89081 Ulm, Germany.ORCID 0000-0002-2737-7495
Hayrettin TumaniDepartment of Neurology, University of Ulm, 89081 Ulm, Germany.
Universität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma exchange (PE) and immunoadsorption (IA) are frequently used for treatment of various autoimmune-mediated neurological diseases, including multiple sclerosis (MS), chronic inflammatory demyelinating polyneuropathy (CIDP), and Guillain-Barré syndrome (GBS). Although both methods are generally regarded as well-tolerated treatment options, evidence for safety and tolerability is low for most indications and largely relies on small case series. In this study, we retrospectively analysed adverse events (AEs) and laboratory changes in 284 patients with various neurological indications who received either PE (

Indexed as

chronic inflammatory demyelinating polyneuropathyimmunoadsorptionmultiple sclerosisneurological diseasestherapeutic plasma exchange

Identifiers

PMID32899499
PMCPMC7565027
OpenAlexW3083714484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.